Results 211 to 220 of about 164,248 (309)

Functional and biochemical protection by combined N-acetylcysteine and D-methionine in guinea pig noise-induced hearing loss. [PDF]

Head Face Med
Wu PH, Cheng N, Lo WC, Chang CM, Cheng PW, Liu SH.   +5 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Physiological and immunological aspects of asthma: the guinea pig (Cavia porcellus) as a model of allergic asthma. [PDF]

Lab Anim Res
Pacheco-Alba I, Alvarez-González M.
europepmc   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Expression and Localization of a New Parvovirus-Derived Protein in the Guinea Pig. [PDF]

Viruses
Osega CE, Bustos FJ, Bronfman FC, Gifford RJ, Arriagada G.   +4 more
europepmc   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

Optogenetic Infection and Optical Stimulation: A Study on Auditory Responses in Guinea Pig Cochlear Neurons. [PDF]

J Otol
Liu C, Yu N.
europepmc   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Reassessment of mechanical restitution in guinea pig cardiomyocytes through refined computational modelling. [PDF]

Sci Rep
Pásek M, Nováková M.
europepmc   +1 more source