Results 221 to 230 of about 882,144 (398)

EXPERIMENTAL SHIGELLA INFECTIONS: CHARACTERISTICS OF A FATAL INFECTION PRODUCED IN GUINEA PIGS [PDF]

open access: bronze, 1958
Samuel B. Formal   +3 more
openalex   +1 more source

Continuous Intravenous Infusion of Hepatocyte Growth Factor Promotes the Development of a Fibrolytic Phenotype in Hepatic Macrophages and Stellate Cells in a Rat Model of Bile Duct Ligation

open access: yesHepatology Research, EarlyView.
This study demonstrates that continuous intravenous infusion of hepatocyte growth factor can significantly reduce liver fibrosis in rats. This treatment promotes hepatocyte regeneration and reduces harmful inflammation, offering promising potential as a therapy for liver cirrhosis in humans. ABSTRACT Aim Liver cirrhosis is a severe condition that often
Oki Taniyama   +15 more
wiley   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

CD59, Disulphide‐Locked Human C9 and Horse C9 Inhibit Human Membrane Attack Complex Assembly by Similar Mechanisms

open access: yesImmunology, EarlyView.
The membrane attack complex (MAC) is formed by the stepwise assembly of five proteins: C5b, C6, C7, C8 and C9. MAC plays a key role in driving inflammation in numerous diseases. This study compares the inhibitory mechanisms of MAC assembly by soluble CD59 (sCD59), a disulphide‐locked C9 mutant (C9lock) and horse C9 (HoC9).
Rebekah S. Cooke   +5 more
wiley   +1 more source

The Experience of Stigma in People Affected by Fibromyalgia: A Metasynthesis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To review the qualitative literature regarding how people with fibromyalgia experience and are impacted by stigma. Design A systematic review and metasynthesis of qualitative studies was conducted following the Thomas and Harden method. Methods The electronic databases PubMed, CINAHL, PsycInfo, Embase and Scopus were queried (September ...
Benedetta Colombo   +3 more
wiley   +1 more source

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