Results 31 to 40 of about 380,579 (360)
Unlike other rodents, guinea pigs (Cavia porcellus) have evolutionarily lost their capacity to synthesize vitamin C (ascorbate) de novo and, like several non-human primates and humans, rely on dietary intake and glutathione-dependent recycling to cope ...
Lorenzo Bertolone+8 more
doaj +1 more source
Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action [PDF]
A series of dibasic des-hydroxy β2 receptor agonists has been prepared and evaluated for potential as inhaled ultra-long acting bronchodilators. Determination of activities at the human β-adrenoreceptors demonstrated a series of highly potent and ...
Alcaraz L.+26 more
core +2 more sources
Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models
Asthma is a common respiratory disease associated with airway hyperresponsiveness (AHR), airway inflammation and mast cell (MC) accumulation in the lung. Monensin, an ionophoric antibiotic, has been shown to induce apoptosis of human MCs. The aim of this
Jielu Liu+6 more
doaj +1 more source
Functional evolution of the feeding system in rodents [PDF]
The masticatory musculature of rodents has evolved to enable both gnawing at the incisors and chewing at the molars. In particular, the masseter muscle is highly specialised, having extended anteriorly to originate from the rostrum.
Cox, Philip G.+7 more
core +1 more source
POLYMORPHISM OF THE ACINI IN SUBLINGUAL GLAND IN SOME SPECIES OF RODENTS - MORPHOLOGICAL STUDY
Salivary glands are a feature of terrestrial species, their structure being different depending on the species and diet. In special literature we did not found informations about the acini polymorphism in sublingual gland, therefore we consider it ...
Bianca Matosz+5 more
doaj +1 more source
Coccidiosis in guinea-pigs [PDF]
The attention of laboratory workers is drawn to the possibility of coccidiosis as a cause of death in guinea-pigs. The purchase of a number of guinea-pigs infected with this protozoon was followed by 12 deaths when these animals were injected with material for diagnostic purposes.
A. E. Wright, P. A. Ellis
openaire +3 more sources
A 2-D guinea pig lung proteome map
Guinea pigs represent an important model for a number of infectious and non-infectious pulmonary diseases. The guinea pig genome has recently been sequenced to full coverage, opening up new research avenues using genomics, transcriptomics and proteomics ...
Simone Schuller+5 more
doaj +1 more source
In this short paper we examine, with lightness and from a semiotic point of view, the different meanings that can be attributed to the guinea pig.
openaire +1 more source
Effect of anticomplement agent K-76 COOH in hamster-to-rat and guinea pig- to-rat xenotransplantation [PDF]
In normal rats, the xenobiotic K76 inhibited the C5 and probably the C2 and C3 steps of complement and effectively depressed classical complement pathway activity, alternative complement pathway activity, and the C3 complement component during and well ...
Adachi+41 more
core +2 more sources
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi+8 more
wiley +1 more source