Results 51 to 60 of about 360,883 (358)

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

Guinea pig apolipoprotein C-II: expression in E. coli, functional studies of recombinant wild-type and mutated variants, and distribution on plasma lipoproteins

open access: yesJournal of Lipid Research, 1997
Guinea pig apolipoprotein C-II (apoC-II) lacks four amino acid residues in the amino-terminal, lipid-binding part compared to apoC-II from other mammalian species (Andersson et al. 1991. J. Biol. Chem. 266: 4074-4080).
Y Andersson   +5 more
doaj  

Immunoglobulin genomics in the guinea pig (Cavia porcellus). [PDF]

open access: yesPLoS ONE, 2012
In science, the guinea pig is known as one of the gold standards for modeling human disease. It is especially important as a molecular and cellular biology model for studying the human immune system, as its immunological genes are more similar to human ...
Yongchen Guo   +7 more
doaj   +1 more source

Application of Isolated Guinea Pig Ileum Method for Detection of Histamine Substances in Osteopeptide Injections

open access: yesShiyan dongwu yu bijiao yixue, 2022
ObjectiveTo evaluate the detection of the histamine substances in osteopeptide injections by the isolated guinea pig ileum method, and to explore the feasibility of replacing cat depressor substances method.MethodsAccording to the 2020 edition of Chinese
WU Chang   +7 more
doaj   +1 more source

Perubahan Tinggi Sel Epitelium Villi Ventrikulus Marmut (Cavia porcellus L.) Setelah Pemberian Teh Hijau [PDF]

open access: yes, 2014
The research of the of Guniea Pig Ventriculus Villi Epithelium Cell Height After Was Given With Green Tea is aimed to know the effect of green tea on ventriculus villi epithelium cell height of female guinea pig.
Kasiyati, Kasiyati, Muliani, Hirawati
core   +1 more source

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

open access: yes, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma   +3 more
core   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

open access: yesAdvanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu   +10 more
wiley   +1 more source

Conductance Changes of Na+ Channels during the Late Na+ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes

open access: yesPharmaceuticals, 2023
Late sodium current (INa,late) is an important inward current contributing to the plateau phase of the action potential (AP) in the mammalian heart. Although INa,late is considered as a possible target for antiarrhythmic agents, several aspects of this ...
Balázs Horváth   +8 more
doaj   +1 more source

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]

open access: yes, 1987
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core  

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

open access: yesAdvanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu   +8 more
wiley   +1 more source

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