Results 51 to 60 of about 380,579 (360)

Immunoglobulin genomics in the guinea pig (Cavia porcellus). [PDF]

PLoS ONE, 2012
In science, the guinea pig is known as one of the gold standards for modeling human disease. It is especially important as a molecular and cellular biology model for studying the human immune system, as its immunological genes are more similar to human ...
Yongchen Guo, Yonghua Bao, Qingwen Meng, Xiaoxiang Hu, Qingyong Meng, Liming Ren, Ning Li, Yaofeng Zhao   +7 more
doaj   +1 more source

Upper-Room Ultraviolet Light and Negative Air Ionization to Prevent Tuberculosis Transmission [PDF]

, 2009
Background Institutional tuberculosis (TB) transmission is an important public health problem highlighted by the HIV/AIDS pandemic and the emergence of multidrug- and extensively drug-resistant TB.
A. Roderick Escombe, Alland, Altman, Armando Gonzalez, Arnold, Bailey Mitchell, Balasubramanian, Basu, Bock, Brubacher, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine Noakes, David A. J Moore, Dwyer, Eduardo Ticona, Escombe, Escombe, Escombe, First, First, First, Fletcher, Gandhi, Gast, Iseman, Jensen, Jon S Friedland, Joshi, Kerr, Ko, Ko, Macher, Marcos Navincopa, Menzies, Mitchell, Mitchell, Mohle-Boetani, Moore, Nardell, Nardell, Nardell, Nardell, Nicas, Noakes, Pai, Patricia Sheen, Peter Wilson, Richardson, Riley, Riley, Riley, Riley, Riley, Riley, Robert H Gilman, Rocio Ramirez, Rudnick, Seo, Stead, Talbot, Valway, Willi Quino, Xu, Xu   +65 more
core   +6 more sources

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen, Chenhao Che, Lingjie Wu, Changjie Sun, Dongming Xu, Qinyang Hua, Yunzhong Zhang, Yi‐Quan Tang, Peng Shi, Shan Sun   +9 more
wiley   +1 more source

Karyotype of Hairless Guinea pig [PDF]

Journal of Sciences, Islamic Republic of Iran, 2013
Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied ...
fatemeh Todehdehghani, Mohammah hassan motedayen, Shohreh Teimorzadeh   +2 more
doaj  

Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]

, 1963
Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
core   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Conductance Changes of Na⁺ Channels during the Late Na⁺ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes

Pharmaceuticals, 2023
Late sodium current (INa,late) is an important inward current contributing to the plateau phase of the action potential (AP) in the mammalian heart. Although INa,late is considered as a possible target for antiarrhythmic agents, several aspects of this ...
Balázs Horváth, Zsigmond M. Kovács, Csaba Dienes, József Óvári, Norbert Szentandrássy, János Magyar, Tamás Bányász, András Varró, Péter P. Nánási   +8 more
doaj   +1 more source

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig [PDF]

, 2018
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ...
Hedley, J, Murphy, B, Priestnall, S L, Stapleton, N, Wong, H E   +4 more
core   +1 more source

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li, Eduardo H. Gilglioni, Wadsen St‐Pierre‐Wijckmans, Leila Hosseinzadeh, Christelle Veyrat‐Durebex, Sumeet Pal Singh, Roberto Coppari, Latifa Bakiri, Esteban N. Gurzov   +8 more
wiley   +1 more source