Results 61 to 70 of about 144,138 (264)

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Ultrastructural and Chemical Composition of Dentin and Enamel in Lab Animals [PDF]

Journal of Dentistry, 2019
Statement of the Problem: Human tooth is clinically the most appropriate material that can be used for in-vitro dental research. However, there are limitations and drawbacks for using human teeth.
Ali Dehghani Nazhvani, Habib Dehghanpour Frashah, Pardis Haddadi, Fatemeh Dehghani Nazhvani   +3 more
doaj  

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

Epilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez, Mustafa Q. Hameed, Yongho Choe, Gabrielle E. McGinty, Amanda M. Liebhardt, Rui Lin, Benjamin Hui, Yini Liang, David J. Arce, Henry H. C. Lee, Mustafa Sahin, Alexander Rotenberg   +11 more
wiley   +1 more source

Antibody kinetics against tetanus toxoid before and after primary vaccination of foals

Equine Veterinary Journal, EarlyView.
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich, Monica Venner, Bettina Wagner   +2 more
wiley   +1 more source

Rickettsial infection in Amblyomma cajennense ticks and capybaras (Hydrochoerus hydrochaeris) in a Brazilian spotted fever-endemic area

Parasites & Vectors, 2014
Background Brazilian spotted fever (BSF), caused by the bacterium Rickettsia rickettsii, is the deadliest spotted fever of the world. In most of the BSF-endemic areas, capybaras (Hydrochoerus hydrochaeris) are the principal host for the tick Amblyomma ...
Felipe S Krawczak, Fernanda A Nieri-Bastos, Fernanda P Nunes, João F Soares, Jonas Moraes-Filho, Marcelo B Labruna   +5 more
doaj   +1 more source

Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs

Frontiers in Microbiology, 2019
Here, we have established an antigen-specific single B cell sorting and monoclonal antibody (mAb) cloning platform for analyzing immunization- or viral infection-elicited antibody response at the clonal level in guinea pigs.
Lin Lei, Karen Tran, Yimeng Wang, James J. Steinhardt, Yongli Xiao, Chi-I Chiang, Richard T. Wyatt, Richard T. Wyatt, Yuxing Li, Yuxing Li   +9 more
doaj   +1 more source

Evaluation of a new immunoassay for measuring equine serum insulin and plasma adrenocorticotrophic hormone: A method comparison study

Equine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) and pituitary pars intermedia dysfunction (PPID) are common equine endocrinopathies detected by measurement of circulating insulin and adrenocorticotrophic hormone (ACTH) concentrations. Different assays may yield variable results, limiting comparability.
Nicola J. Menzies‐Gow, Perrine Cosin, Valerie Guyot   +2 more
wiley   +1 more source

Comparative analysis of rodent lens morphometrics and biomechanical properties

Frontiers in Ophthalmology
IntroductionProper ocular lens function requires biomechanical flexibility, which is reduced during aging. As increasing lens size has been shown to correlate with lens biomechanical stiffness in aging, we tested the hypothesis that whole lens size ...
Sepideh Cheheltani, Sadia T. Islam, Heather Malino, Kalekidan Abera, Sandeep Aryal, Karen Forbes, Justin Parreno, Justin Parreno, Velia M. Fowler, Velia M. Fowler   +9 more
doaj   +1 more source

Frequency of Owner-Reported Bacterial Infections in Pet Guinea Pigs

Animals, 2019
Domestic guinea pigs suffer morbidity and mortality due to a range of bacterial infections amongst other causes. Microorganisms such as Bordetella bronchiseptica and Streptococcus pneumoniae are commonly implicated in respiratory disease; however, there ...
Shannon Roberts-Steel, James A. Oxley, Aisling Carroll, Alison P. Wills   +3 more
doaj   +1 more source

Effects of Lactic Acid Bacteria and Yeasts on Growth Performance, Intestinal Health, and Organ Morphometry of Broiler Chickens

Food Safety and Health, EarlyView.
The fermentation of molasses‐vinasse with lactic acid bacteria and yeasts improves growth, intestinal health, digestive, and immune organs in chickens, promoting their productive performance and organic development. ABSTRACT This study evaluated the probiotic effects of lactic acid bacteria and yeasts on productive parameters, intestinal health, and ...
José Miranda‐Yuquilema, Fabian Astudillo‐Riera, Juan Taboada‐Pico, Mercy Cuenca‐Condo, Kevin Astudillo‐Vallejo   +4 more
wiley   +1 more source