Results 1 to 10 of about 707,186 (264)

Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs

Investigative Ophthalmology and Visual Science, 2021
Purpose The development of myopia in guinea pigs can be inhibited by attenuating scleral hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP through surgical and pharmacological methods to determine the effect on myopia
Xuan Zhou, Sen Zhang, Fan Yang, Yaozhen Yang, Qing-Yuan Huang, Chengjie Huang, J. Qu, Xiangtian Zhou   +7 more
semanticscholar   +1 more source

Effects of Red, Green and Black Pepper on Intestinal Motility and Post-Prandial Bicarbonate Concentration in Guinea Pigs. [PDF]

Niger Med J
Charles C, Obia O, Emmanuel FD, Ogba A, Ojeka SO.   +4 more
europepmc   +2 more sources

Intranasal infection and contact transmission of Zika virus in guinea pigs

Nature Communications, 2017
Zika virus (ZIKV) is primarily transmitted to humans through mosquito bites or sexual contact. The excretion and persistence of contagious ZIKV in various body fluids have been well documented in ZIKV patients; however, the risk of direct contact ...
Yongqiang Deng, Na-Na Zhang, Xiao-Feng Li, Ya-Qing Wang, Min Tian, Y. Qiu, Jun-Wan Fan, Jia-Nan Hao, Xingyao Huang, Hao-Long Dong, Hang Fan, Yu-guang Wang, Fu-chun Zhang, Y. Tong, Zhiheng Xu, C. Qin   +15 more
semanticscholar   +1 more source

MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs

Nature Communications, 2015
Toxin–antitoxin (TA) systems are highly conserved in members of the Mycobacterium tuberculosis (Mtb) complex and have been proposed to play an important role in physiology and virulence.
P. Tiwari, Garima Arora, M. Singh, Saqib Kidwai, O. Narayan, Ramandeep Singh   +5 more
semanticscholar   +1 more source

A FILTERABLE VIRUS PRESENT IN THE SUBMAXILLARY GLANDS OF GUINEA PIGS

Journal of Experimental Medicine, 1926
In the lesions of herpes simplex and similar conditions due to filterable viruses, cells are present which show characteristic alterations, particularly in the nucleus. The nucleus of these cells contains a mass which stains with acid dyes.
R. Cole, A. Kuttner
semanticscholar   +1 more source

Gap prepulse inhibition and auditory brainstem-evoked potentials as objective measures for tinnitus in guinea pigs

Frontiers in Systems Neuroscience, 2012
Tinnitus or ringing of the ears is a subjective phantom sensation necessitating behavioral models that objectively demonstrate the existence and quality of the tinnitus sensation. The gap detection test uses the acoustic startle response elicited by loud
Susanne Dehmel, Daniela A. Eisinger, S. Shore   +2 more
semanticscholar   +1 more source

Ebola GP-Specific Monoclonal Antibodies Protect Mice and Guinea Pigs from Lethal Ebola Virus Infection

PLoS Neglected Tropical Diseases, 2012
Ebola virus (EBOV) causes acute hemorrhagic fever in humans and non-human primates with mortality rates up to 90%. So far there are no effective treatments available.
X. Qiu, L. Fernando, P. Melito, J. Audet, J. Audet, Heinz Feldmann, Heinz Feldmann, G. Kobinger, G. Kobinger, J. Alimonti, J. Alimonti, Steven M. Jones, Steven M. Jones   +12 more
semanticscholar   +1 more source

A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

BMC Genomics, 2012
BackgroundGuinea pig (Cavia porcellus) is an important model for human intestinal research. We have characterized the faecal microbiota of 60 guinea pigs using Illumina shotgun metagenomics, and used this data to compile a gene catalogue of its prevalent
F. Hildebrand, T. Ebersbach, H. Nielsen, Xiaoping Li, S. B. Sonne, Marcelo Bertalan, P. Dimitrov, L. Madsen, J. Qin, Jun Wang, J. Raes, K. Kristiansen, T. R. Licht   +12 more
semanticscholar   +1 more source

Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia.

Investigative Ophthalmology and Visual Science, 2019
Purpose The purpose of this study was to study changes in choroidal thickness (ChT) and choroidal blood perfusion (ChBP), and the correlation between them, in guinea pig myopia. Methods The reliability of optical coherence tomography angiography (OCTA)
Sen Zhang, Guoyun Zhang, Xuan Zhou, Renchang Xu, Siyao Wang, Zhenqi Guan, Juan Lu, Nethrajeith Srinivasalu, M. Shen, Zi Jin, J. Qu, Xiangtian Zhou   +11 more
semanticscholar   +1 more source

Evidence for Oxidative Stress and Defective Antioxidant Response in Guinea Pigs with Tuberculosis

PLoS ONE, 2011
The development of granulomatous inflammation with caseous necrosis is an important but poorly understood manifestation of tuberculosis in humans and some animal models.
G. Palanisamy, N. Kirk, David F. Ackart, Crystal A. Shanley, I. Orme, R. Basaraba   +5 more
semanticscholar   +1 more source