Results 101 to 110 of about 804,908 (352)

The evolution of sensitive periods beyond early ontogeny: Bridging theory and data

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Sensitive periods, in which experiences have a large impact on phenotypic development, are most common early in ontogeny. Yet, they may also occur at later ontogenetic stages, such as adolescence.
Nicole Walasek   +2 more
wiley   +1 more source

Soil and microbial responses to wild ungulate trampling depend more on ecosystem type than trampling severity

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Physical trampling is a ubiquitous activity of walking vertebrates, but is poorly understood as a mechanism impacting biogeochemical cycling in soil. Lack of detailed knowledge of soil abiotic–biotic interactions underlying trampling effects, and the primary sources of ...
G. Adam Meyer   +3 more
wiley   +1 more source

Senescent Microglia Mediate Neuroinflammation‐Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1

open access: yesAging Cell, EarlyView.
In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu   +8 more
wiley   +1 more source

Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans

open access: yesScience Translational Medicine, 2018
Kendra L Marks   +6 more
semanticscholar   +1 more source

Differential Effects of Liver Regeneration on Aging‐Related Changes in Gene Expression and Metabolic Function

open access: yesAging Cell, EarlyView.
The age‐specific gene expression status of aged mouse hepatocytes is mostly resolved and rejuvenated when liver regeneration is completed; whereas the age‐specific intracellular metabolic status detected in the liver of aged mice is largely maintained and not rejuvenated even after liver regeneration is completed.
Ryo Murayama   +9 more
wiley   +1 more source

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