Results 91 to 100 of about 113,247 (259)
Open Veterinary JournalBackground: Improving the nutritional quality and productivity of guinea pigs is a priority in Peruvian livestock production, driving the search for sustainable feeding strategies.
Cesar A. Piscoya Vargas +7 more
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Generative artificial intelligence in higher education: Emotional tensions and ethical declaration
British Journal of Educational Technology, EarlyView.Abstract The increasing use of Generative Artificial Intelligence (GenAI) tools such as ChatGPT in higher education has raised questions about authorship, ethical responsibility, and academic transparency. While institutional guidelines exist, many remain vague and ineffective, leaving students to interpret disclosure obligations on their own.
Yao Qu, Hui En Loo, Jue Wang
wiley +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
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British Journal of Pharmacology, EarlyView.Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley +1 more source
Livestock guinea pigs: a scoping review from a One Health perspective
Frontiers in Veterinary ScienceThe guinea pig (Cavia porcellus) has been raised in the Andean Region of South America since ancient times, valued not only for its nutritional contributions but also for its cultural and religious significance.
Mauricio Salas-Rueda +5 more
doaj +1 more source
Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm
British Journal of Pharmacology, EarlyView.Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio +11 more
wiley +1 more source
A comparison of virulence of intraperitoneal infection of Burkholderia mallei strains in guinea-pigs
Archives of Razi Institute, 2015 Male guinea pigs show high susceptibility to Burkholderia mallei and have been used as animal models in glanders studies. The purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. We present here the histological changes
Eslampanah, M. +2 more
doaj
British Journal of Pharmacology, EarlyView.Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock +9 more
wiley +1 more source