Results 101 to 110 of about 113,247 (259)
Background This study aimed to develop a guinea pig model of concurrent allergic rhinitis and asthma. Methods Thirty-three guinea pigs were randomly divided into the control group and the experimental group.
Feng Xu +3 more
doaj +1 more source
Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder
Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka +4 more
wiley +1 more source
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding
Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh +7 more
wiley +1 more source
Lilit Garibyan, MD, PhD +1 more
openaire +3 more sources
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke +5 more
wiley +1 more source
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó +4 more
wiley +1 more source
The trigeminal nerve of the rat (Rattus norvegicus) and its relationship with different masticatory muscles. dig, digastric nerve; ep, external pterygoid nerve; ip, internal pterygoid nerve; maadm, branch of the masseteric nerve for the anterior deep masseter; mapdm, branches of the masseteric nerve for the posterior deep masseter; masm, branch of the ...
Lionel Hautier +5 more
wiley +1 more source
Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve
Using tissue clearing and light‐sheet microscopy methods, we visualized the 3D mesoscopic arrangement of neural tracts, blood vessels and neurons within the adult human superior hypogastric plexus and hypogastric nerves, identifying the latter to contain thousands of neuronal cells bodies embedded along its entire length.
Kayleigh S. Scotcher +4 more
wiley +1 more source

