Results 151 to 160 of about 311,598 (350)

miR-92b-3p protects retinal tissues against DNA damage and apoptosis by targeting BTG2 in experimental myopia

open access: yesJournal of Translational Medicine
Background Myopia is one of the eye diseases that can damage the vision of young people. This study aimed to explore the protective role of miR-92b-3p against DNA damage and apoptosis in retinal tissues of negative lens-induced myopic (LIM) guinea pigs ...
Jinpeng Liu   +10 more
doaj   +1 more source

Soil and microbial responses to wild ungulate trampling depend more on ecosystem type than trampling severity

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Physical trampling is a ubiquitous activity of walking vertebrates, but is poorly understood as a mechanism impacting biogeochemical cycling in soil. Lack of detailed knowledge of soil abiotic–biotic interactions underlying trampling effects, and the primary sources of ...
G. Adam Meyer   +3 more
wiley   +1 more source

An Explanation of Path Analysis and Recommendations for Best Practice

open access: yesContemporary Accounting Research, EarlyView.
ABSTRACT Path analysis has become increasingly popular, but many studies do not show a deep understanding of how path analysis works or the assumptions on which it relies. In this paper, we explain that path analysis is statistically equivalent to either OLS when the researcher assumes uncorrelated errors, or instrumental variable (IV) estimation when ...
Clive Lennox, Carmen Payne‐Mann
wiley   +1 more source

Chronic Low‐Level Lead Exposure Causes Auditory Impairment and Accelerates the Progression of Age‐Related Hearing Loss in C57BL/6J Mice

open access: yesAging Cell, EarlyView.
Chronic low‐concentration lead exposure accelerates the development of ARHL. Lead exposure mediates damage to cochlear sensory cells via the mitochondrial protease LONP1, leading to irreversible hearing loss. ABSTRACT Heavy metal ion exposure has become a global public health concern.
Xue Bai   +10 more
wiley   +1 more source

Antitussive Effect of Plantago lanceolata in Guinea Pigs [PDF]

open access: green, 2006
Mohammad Hossein Boskabady   +4 more
openalex  

Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model [PDF]

open access: diamond, 2019
Joy Gary   +11 more
openalex   +1 more source

Spatiotemporal Crosstalk Between Oocyte and the Microenvironment Governs Preovulatory Follicle Aging

open access: yesAging Cell, EarlyView.
Preovulatory follicle aging is characterized by two distinct phases—early oocyte protective and late degenerative phases. The degenerative phase involves a positive feedback loop between oocyte mitochondrial dysfunction mediated by a mitochondrial‐localized microprotein PIGBOS, and granulosa cell functional decline through a circular RNA circdlg1 ...
Xin Yi Koh   +7 more
wiley   +1 more source

Ketogenesis is Dispensable for the Metabolic Adaptations to Caloric Restriction

open access: yesAging Cell, EarlyView.
In this study, we demonstrated that metabolic responses to a daily‐fed caloric restriction (CR) protocol remain robust in mice that cannot engage in canonical ketogenesis. This surprising finding is due to mice physiologically adapting to the daily bouts of fasting during CR by downregulating ketone production. ABSTRACT Caloric restriction (CR) extends
Chung‐Yang Yeh   +13 more
wiley   +1 more source

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