Results 151 to 160 of about 279,553 (350)

Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder

open access: yesChildren &Society, EarlyView.
Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka   +4 more
wiley   +1 more source

Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2

open access: yesBMC Pulmonary Medicine
Background This study aimed to develop a guinea pig model of concurrent allergic rhinitis and asthma. Methods Thirty-three guinea pigs were randomly divided into the control group and the experimental group.
Feng Xu   +3 more
doaj   +1 more source

Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis

open access: yesContact Dermatitis, EarlyView.
ABSTRACT Contact dermatitis is an inflammatory disease characterised by skin redness and swelling, oozing of fluid or pus and pain, caused by direct skin contact with an irritant or allergen. Its prevalence has skyrocketed worldwide, probably because human skin is in daily contact with an increasing gamut of irritants and allergens, which should ...
Meital Portugal‐Cohen   +9 more
wiley   +1 more source

Testis‐Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis

open access: yesCell Proliferation, EarlyView.
PDHA2, a testis‐specific subunit of pyruvate dehydrogenase, is required for the conversion of pyruvate to acetyl‐CoA. Its absence results in decreased acetyl‐CoA and precursors for metabolites and energy during spermatogenesis. This results in decreased histone acetylation, defective chromosome structure and moderately reduced crossovers, ultimately ...
Guoqiang Wang   +9 more
wiley   +1 more source

Indigenous Peoples’ human genomic sovereignty: Lessons for Africa

open access: yesDeveloping World Bioethics, EarlyView.
Abstract Human genomics research with indigenous peoples has often been characterised by tension between the ‘western’ science ideologies and indigenous peoples’ cultural beliefs in relation to their human genetic resources and data. This article explores this tension from the lens of the concept of indigenous peoples’ human genomic sovereignty and ...
Faith Kabata
wiley   +1 more source

Fast activity chirp patterns in focal seizures from patients and animal models

open access: yesEpilepsia, Volume 66, Issue 3, Page 621-631, March 2025.
Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque   +6 more
wiley   +1 more source

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