Bioinformatics based design of thermostable virus-like particles-based vaccine for foot-and-mouth disease serotype A and <i>in-vivo</i> evaluation in guinea pigs. [PDF]
Selvaraj DPR +9 more
europepmc +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Effects of the estrous cycle and sex on stress responses in guinea pigs. [PDF]
Nemeth M +3 more
europepmc +1 more source
Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen +2 more
wiley +1 more source
Development of a Hyperopia Animal Model Using Blue Light in Guinea Pigs. [PDF]
Yoo YJ, Hwang JM.
europepmc +1 more source
Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley +1 more source
Prevalence and awareness of obesity and related husbandry practices in Estonian rabbits, guinea pigs, and rats. [PDF]
Pantelejev M, Tõnise K.
europepmc +1 more source
In development, microglia engulfment of hippocampal excitatory synapses is unperturbed in C3‐lacking mice. Peripheral inflammation induces a neuroinflammatory phenotype and synapse loss in the hippocampus independent of complement cascade activation. ABSTRACT A key feature of brain development is the refinement of exuberant synapses, known as synapse ...
Eric W. Salter +9 more
wiley +1 more source
Hexavalent Chromium Oropharyngeal Aspiration Induced Behavior Effects and Essential Metal Dyshomeostasis in Young Hartley Guinea Pigs. [PDF]
Vielee ST +12 more
europepmc +1 more source

