Results 211 to 220 of about 430,792 (252)

Architecture of the cardiac transverse–axial tubular system across different mammalian species

The Journal of Physiology, EarlyView.
Abstract figure legend Mammalian species differ in ventricular TATS architecture, and cytoplasmic distance to the nearest TATS element covaries with lifespan, body mass, and resting heart rate. Abstract Cardiac excitation–contraction coupling relies on a pancellular network of regular cardiomyocyte surface membrane invaginations, termed the transverse ...
Joachim Greiner, Frédéric Sonak, Wesley Dean Jones, Patricia Morais Costa, Josef Madl, Kathrine Albertine Ryeng, Igor R. Efimov, Zafar Iqbal, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +10 more
wiley   +1 more source

Comprehensive characterization of myopic guinea pigs' retina following PI3K/AKT inhibition using a data-independent acquisition dataset on an Orbitrap Exploris 480 mass spectrometer. [PDF]

Data Brief
Xiao H, Xin W, Wong OY, Leung MH, Cheung JK, Lu DQ, Zhou L, Chun RKM, Bian JF, Lam TC.   +9 more
europepmc   +1 more source

Intracellular mechanosensation in intestinal smooth muscle: Piezo1 complexes amplify signalling beyond the surface

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanosensation is not confined to the cell surface. In intestinal smooth muscle Piezo1 is predominantly intracellular (86%), where it forms a nanoscale (<40 nm) complex at the sarcoplasmic reticulum (SR)–plasma membrane junction. Within this sensor–amplifier–effector axis intra‐Piezo1 is the sensor that detects force at the SR,
Geoanna M. Bautista, Declan Manning, Emily C. Lieu, Stephanie I. Ugochukwu, Collin Matsumoto, Joshua P. Tulman, Miguel Martin‐Aragon Baudel, Nuria Daghbouche‐Rubio, Steven J. McElroy, Sal A. Baker, Manuel F. Navedo, L. Fernando Santana   +11 more
wiley   +1 more source

Immunogenicity of an Inactivated DIVA Lumpy Skin Disease Virus Vaccine in Guinea Pigs and Lactating Cows, and Its Effects on Cow Lactation. [PDF]

Vaccines (Basel)
Testa L, Capista S, Serroni A, Iorio M, Ronchi GF, Traini S, Matteo ID, Laguardia C, Profeta F, Palucci C, Caporale M, Saletti MA, Marchegiano A, Pinoni C, Rossi E, Salini R, Aretusi G, Armillotta G, Fanì S, Parolini F, Ventura MD, Mercante MT.   +21 more
europepmc   +1 more source

Erratum: [Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet. [PDF]

Exp Ther Med
Huang L, Ding C, Si X.
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Medetomidine Administration at the Subcutaneous GV20 Acupoint Compared with the Intramuscular Route in Guinea Pigs (Cavia porcellus): Sedation Score, Onset, and Duration of Action. [PDF]

J Am Assoc Lab Anim Sci
Esjaita EI, Fuensalida SE, Giansanti NH, Regner PI, Bernal LD, García-Blanco F, Otero PE, Waxman S.   +7 more
europepmc   +1 more source

‘All of It Was Hard. And All of It Was Necessary’: A Reflexive Thematic Analysis of Service User Experience of Group Schema Therapy for Borderline Personality Disorder

Counselling and Psychotherapy Research, Volume 26, Issue 4, December 2026.
ABSTRACT Background Group Schema Therapy is supported by a good evidence base as an effective treatment for Borderline Personality Disorder. Though we are continuing to learn about its mechanisms of change and how it is experienced, published research has not yet explored the experiences of service users in UK Tier 3 mental health services.
Kathleen McGlynn, Emma Smith
wiley   +1 more source

Effect of Repeated Medium-Dose Red Laser Irradiation on Ocular Tissues in Guinea Pigs. [PDF]

Invest Ophthalmol Vis Sci
Song QQ, Xu W, Li SM, Wang N, Kang MT.
europepmc   +1 more source

Fampridine for Symptomatic Treatment in Chronic Inflammatory Demyelinating Polyneuropathy: A Randomized, Double‐Blinded, Placebo‐Controlled Crossover Study

Journal of the Peripheral Nervous System, Volume 31, Issue 4, December 2026.
ABSTRACT Background and Aims Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is an immune‐mediated neuropathy that may cause persistent disability despite immunoglobulin treatment. Ion channel dysfunction has been demonstrated in CIDP, but no therapies specifically target this mechanism.
Peter Nørregaard Hansen, Lars Markvardsen, Hatice Tankisi, Henning Andersen, Thomas Krøigård, Søren Sindrup   +5 more
wiley   +1 more source