Results 51 to 60 of about 311,598 (350)

Vaccination with BCGΔBCG1419c protects against pulmonary and extrapulmonary TB and is safer than BCG

Scientific Reports, 2021
A single intradermal vaccination with an antibiotic-less version of BCGΔBCG1419c given to guinea pigs conferred a significant improvement in outcome following a low dose aerosol exposure to M.
Michel de Jesús Aceves-Sánchez, Mario Alberto Flores-Valdez, César Pedroza-Roldán, Elizabeth Creissen, Linda Izzo, Fabiola Silva-Angulo, Clinton Dawson, Angelo Izzo, Helle Bielefeldt-Ohmann, Cristian Alfredo Segura-Cerda, Wendy López-Romero, Jorge Bravo-Madrigal, Jorge Alberto Barrios-Payán, Miguel Ángel de la Cruz, Miguel Ares, María Guadalupe Jorge-Espinoza   +15 more
doaj   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Condition of pro-oxidant and antioxidant systems in guinea pigs’ lungs under the condition of immobilization stress

Journal of Education, Health and Sport, 2017
We have investigated the results of alterations in indices of pro-oxidant (conjugated diene and malondialdehyde ) and antioxidant (superoxide dismutase, ceruloplasmin, catalase) systems in guinea pigs’ lungs  under the conditions of immobilization ...
Mykhailo Stepanovych Reheda, Marta Yevhenivna Kovalska, Mariana Ljubomurivna Baida   +2 more
doaj   +3 more sources

Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]

, 1963
Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Study the effect of chamomile on hyperlipidaemias in Guinea pigs

Kufa Journal for Veterinary Medical Sciences, 2012
    In this study used ( 40 ) guinea pigs males Divided into Two 2 group and this Two groups Divided into Two sub groups .     The Effect of 5% aqueous of matricaria chamomile ( 5ml/kg ) on Cholesterol and triglyceride level was studied in normal and ...
Ahmed J. AL-Bayati
doaj   +1 more source

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig [PDF]

, 2018
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ...
Hedley, J, Murphy, B, Priestnall, S L, Stapleton, N, Wong, H E   +4 more
core   +2 more sources

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Spontaneous behavior in noise and silence: a possible new measure to assess tinnitus in guinea pigs

Frontiers in Neurology, 2014
This study describes two experiments that were conducted in search for a behavioral paradigm to test for tinnitus in guinea pigs. Conditioning paradigms are available to determine the presence of tinnitus in animals and are based on the assumption that ...
Amarins Nieske Heeringa, Amarins Nieske Heeringa, Martijn Johannus H. Agterberg, Martijn Johannus H. Agterberg, Pim evan Dijk, Pim evan Dijk   +5 more
doaj   +1 more source

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. [PDF]

, 1995
Experiments were designed to study the effect of systemically administered IL-5 on local eosinophil accumulation induced by the intradermal injection of the chemokine eotaxin in the guinea pig.
Collins, PD, Griffiths-Johnson, DA, Jose, PJ, Marleau, S, Williams, TJ   +4 more
core   +2 more sources