Results 31 to 40 of about 62,774 (121)

Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation

Gut Microbes
Gut bacteria play key roles in intestinal physiology, via the secretion of diversified bacterial effectors. Many of these effectors remodel the host proteome, either by altering transcription or by regulating protein post-translational modifications ...
Léa Loison, Marion Huré, Benjamin Lefranc, Jérôme Leprince, Christine Bôle-Feysot, Moïse Coëffier, David Ribet   +6 more
doaj   +1 more source

Therapeutic Effects of Baicalin on Diseases Related to Gut–Brain Axis Dysfunctions

Molecules, 2023
The gut–brain axis is an active area of research. Several representative diseases, including central nervous system disorders (Alzheimer’s disease, Parkinson’s disease, and depression), metabolic disorders (obesity-related diseases), and intestinal ...
Qichao Hu, Shuyu Hou, Baoyi Xiong, Yueqiang Wen, Jundong Wang, Jinhao Zeng, Xiao Ma, Fang Wang   +7 more
doaj   +1 more source

Sex-dependent effects of a high fat diet on metabolic disorders, intestinal barrier function and gut microbiota in mouse

Scientific Reports
Obesity is often associated with sex-dependent metabolic complications, in which altered intestinal barrier function and gut microbiota contribute. We aimed to characterize in mice the sex-dependent effects of a high fat diet on these parameters.
Candice Lefebvre, Adam Tiffay, Charles-Edward Breemeersch, Virginie Dreux, Christine Bôle-Feysot, Charlène Guérin, Jonathan Breton, Elise Maximin, Magali Monnoye, Pierre Déchelotte, Véronique Douard, Alexis Goichon, Moïse Coëffier   +12 more
doaj   +1 more source

Functional roles of the microbiota-gut-brain axis in Alzheimer’s disease: Implications of gut microbiota-targeted therapy

Translational Neuroscience, 2021
Increasing scientific evidence demonstrates that the gut microbiota influences normal physiological homeostasis and contributes to pathogenesis, ranging from obesity to neurodegenerative diseases, such as Alzheimer’s disease (AD).
Zhong Si-Ran, Kuang Qi, Zhang Fan, Chen Ben, Zhong Zhen-Guo   +4 more
doaj   +1 more source

Caloric labels do not influence taste pleasantness and neural responses to erythritol and sucrose

NeuroImage
Introduction: The beneficial effects of substituting sugar with non-caloric sweeteners (NCSs) remain uncertain due to the mismatch between their rewarding sweet taste and lack of energy content.
Aleksandra Budzinska, Laura Byl, Fabienne Teysseire, Emilie Flad, Patrick Dupont, Bettina Wölnerhanssen, Anne Christin Meyer-Gerspach, Lukas Van Oudenhove, Nathalie Weltens   +8 more
doaj   +1 more source

Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin in preclinical models

Nature Communications
Intestinal fibrosis is a common complication in inflammatory bowel diseases with no specific therapy. Because mineralocorticoid receptor antagonism prevented inflammation and fibrosis in extra-intestinal organs, we aimed to evaluate mineralocorticoid ...
Asma Amamou, Mathilde Leboutte, Jonathan Breton, David Ribet, Pierre-Alain Thiebaut, Christine Bôle-Feysot, Charlène Guérin, Kanhia Aublé, Elise Rebollo, Lise Ratel, Benjamin Bonnard, Alexis Goichon, Louison Leblond, Moutaz Aziz, Elodie Fermant, Frédéric Jaisser, Guillaume Savoye, Rachel Marion-Letellier   +17 more
doaj   +1 more source

Depression among medical students in Bangladesh: a systematic review and meta-analysis protocol on prevalence and associated factors

BMJ Open
Introduction Depression, affecting 350 million people globally, is notably prevalent among medical students, particularly in South Asia, including Bangladesh.
Mantaka Rahman, Imtiaz Abdullah, Nusrat Fatema   +2 more
doaj   +1 more source

Molecular anatomy of the gut-brain axis revealed with transgenic technologies: implications in metabolic research

Frontiers in Neuroscience, 2013
Neurons residing in the gut-brain axis remain understudied despite their important role in coordinating metabolic functions. This lack of knowledge is observed, in part, because labeling gut-brain axis neurons and their connections using conventional ...
Laurent eGautron
doaj   +1 more source

Importance of good hosting: reviewing the bi-directionality of the microbiome-gut-brain-axis

Frontiers in Neuroscience
Gut microorganisms have been shown to significantly impact on central function and studies that have associated brain disorders with specific bacterial genera have advocated an anomalous gut microbiome as the pathophysiological basis of several ...
Carolina F. F. A. Costa, Carolina F. F. A. Costa, Joana Ferreira-Gomes, Joana Ferreira-Gomes, Fernando Barbosa, Benedita Sampaio-Maia, Benedita Sampaio-Maia, Philip W. J. Burnet   +7 more
doaj   +1 more source

Therapeutic role of gut microbiota in lung injury-related cognitive impairment

Frontiers in Nutrition
Lung injury can lead to specific neurocognitive dysfunction, and the “triple-hit” phenomenon may be the key theoretical mechanism for the progressive impairment of lung injury-related cognitive impairment.
Yanxia Cheng, Guangtao Hu, Lin Deng, Yalan Zan, Xia Chen   +4 more
doaj   +1 more source