Results 41 to 50 of about 95,803 (268)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Studying the Role of PTEN in The Gut and Investigating the Gut-Brain Inflammatory Interaction

, 2023
Phosphatase and tensin homolog (Pten) deficiency causes tumorigenesis because Pten opposes PI3k-Akt signaling. However, correlation between Pten deficiency and colon cancer remains unclear due to contradicting studies.
Howe, Cody Scott
core  

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Sex-dependent effects of a high-fat diet on the hypothalamic response in mice

Biology of Sex Differences
Sex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux, Candice Lefebvre, Charles-Edward Breemeersch, Colin Salaün, Christine Bôle-Feysot, Charlène Guérin, Pierre Déchelotte, Alexis Goichon, Moïse Coëffier, Ludovic Langlois   +9 more
doaj   +1 more source

Intestinal epithelial TLR4 knock out induces sex-specific effects on gut barrier and microbiome in an activity-based anorexia model

Gut Microbes
The role of the microbiota‒gut‒brain axis in the pathophysiology of anorexia nervosa has emerged in recent decades. Increased expression of Toll-like receptor 4 (TLR4) has been reported in the intestinal epithelial cells (IEC) of activity-based anorexia (
Colin Salaün, Marion Huré, Charlène Guérin, Christine Bôle-Feysot, Audrey Valentin, Fatima Léon, Sarah Lenoir, Jean-Luc do-Rego, Jean-Claude do-Rego, Ludovic Langlois, David Ribet, Najate Achamrah, Moïse Coëffier   +12 more
doaj   +1 more source

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

Advanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae, Kyung‐Sub Kim, Gyeong‐Seok Hwang, Jun‐Seok Shim, Sung‐Woo Kim, Yong‐Wu Kim, Jieun Han, Jae‐Young Bae, Jae‐Hwan Lee, Minjung Chae, Jooik Jeon, Joo‐Hyeon Park, You‐Jung Park, Ju‐Yong Lee, Sung‐Geun Choi, Min‐Ha Oh, Yong‐Joong Shin, Young‐In Ryu, Ji‐Woo Gu, Seong‐Yu Choi, Jeong‐Yun Sun, Jung Keun Hyun, Myoung‐Ryul Ok, Sang Yup Kim, Edyta Wyszkowska, Ju‐Young Kim, Kang‐Sik Lee, Seung‐Kyun Kang   +27 more
wiley   +1 more source

Epidemiology and risk factors of Alzheimer’s disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis protocol

BMJ Open
Background Alzheimer’s disease (AD) impacts over 55 million individuals worldwide and remains the leading cause of dementia (60–70% of cases). By 2050, South and Southeast Asia are projected to have an older adult population more than double, bearing a ...
Zhahirul Islam, Israt Jahan, Sharmin Sultana, Nowshin Papri, Mantaka Rahman, Imran Hasan, Tamal Saha, Shoma Hayat, Ashiqa Tabassum, Md Abu Jaher Nayeem   +9 more
doaj   +1 more source

Microbiota-gut brain axis involvement in neuropsychiatric disorders [PDF]

, 2019
Introduction: The microbiota-gut brain (MGB) axis is the bidirectional communication between the intestinal microbiota and the brain. An increasing body of preclinical and clinical evidence has revealed that the gut microbial ecosystem can affect ...
Preda A., Tagliabue A., Iannetti, P, Guiducci L., Ferraris, C, Ronchi, Francesca, Luongo G., Striano P., Russo, E, Citraro, R, Selmer, K, Verrotti, A, Albani D., Baldelli, Pietro, Cattaneo, Anna, Carotenuto, Marco, Mainardi P., Tagliabue, A, Spalice A., Guiducci, Letizia, Ferraris C., Zara, F, Spalice, Alberto, Iannone, LF, Carotenuto M., Segata, N, Zimmermann, J, Verrotti, Alberto, Verrotti A., Russo E., Blottiere, HM, Ronchi, F, Guiducci, L, Spalice, A, Selmer, Kaja, Sisodiya, Sanjay, Minetti C., Iannone L. F., Cattaneo, Annamaria, Segata N., Santocchi E., Blottière, Hervé M, Minetti, Carlo, Baldelli, P, Giordano, Carmen, Striano, Pasquale, Petretto, Andrea, Carotenuto, M, Provasi, Stefania, Provasi, S, Russo, Emilio, Albani, D, Belcastro, Vincenzo, Zara, Federico, Zimmermann J., Provasi S., Cattaneo, A, Belcastro, V, Citraro R., Iannetti, Paola, Luongo, G, Iannone, Luigi Francesco, Santocchi, Elisa, Preda, Alberto, Mainardi, Paolo, Segata, Nicola, Cattaneo A., Belcastro V., Zimmermann, Jakob, Giordano C., Tagliabue, Anna, Clarke G., Iannetti P., Ferraris, Cinzia, Giordano, C, Zara F., Minetti, C, Clarke, G, Ronchi F., Baldelli P., Petretto A., Mainardi, P, Sisodiya S., Blottiere, Hervé H, Citraro, Rita, Pedersen S., Pedersen, S, Albani, Diego, Blottiere H. M., Luongo, Gaia, Santocchi, E, Preda, A, Petretto, A, Selmer K., Clarke, Gerard, Sisodiya, S, Pedersen, Sigrid, Striano, Pasquale., Blottière, Hervé M., Cattaneo, Annamaria; id_orcid, Striano, P   +100 more
core   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Interleukin‐10 promoter polymorphisms and haplotypes in patients with Guillain–Barré syndrome

Annals of Clinical and Translational Neurology
Objective Interleukin‐10 (IL‐10) is a multifunctional cytokine that exerts both pro‐ and anti‐inflammatory effects on the immune system as well as in the pathogenesis of Guillain–Barré syndrome (GBS).
Shoma Hayat, Asaduzzaman Asad, Moriam Akter Munni, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Israt Jahan, Md. Zakir Hossain Howlader, Quazi Deen Mohammad, Zhahirul Islam   +8 more
doaj   +1 more source