Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source
Total flavonoids from <i>Abelmoschus manihot</i> (L.) improve diabetes nephropathy by regulating the gut-kidney axis. [PDF]
Yu H, Liu Y, Gu HF, Tang W, Li N.
europepmc +1 more source
Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li +11 more
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We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Pediatric and adult point of view on the gut-kidney axis in CKD. [PDF]
Holle J, Behrens F, Koppe L.
europepmc +1 more source
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala +6 more
wiley +1 more source
<i>Lactiplantibacillus plantarum</i> HY7718 Modulates Gut-Kidney Axis-Associated Inflammation, Gastrointestinal Dysfunction, and Gut Microbiota in Adenine-Induced Chronic Kidney Disease Mice. [PDF]
Kim H +4 more
europepmc +1 more source
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood +3 more
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Retraction: Commentary: One mechanism of Sishen Pill on diarrhea with kidney Yang deficiency syndrome: influencing metabolic function by intestinal microorganisms and enzyme activity mediates the gut-kidney axis. [PDF]
Frontiers Editorial Office.
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Abstract Objectives Immune dysregulation in paediatric portal hypertension (PHT) is poorly understood. We aimed to characterise T cell phenotype and function and circulating immune mediators in children with PHT according to disease aetiology. Methods Forty‐four children with PHT (27 chronic liver disease [CLD]‐related and 17 portal vein thrombosis ...
Tengfei Si +11 more
wiley +1 more source

