Results 201 to 210 of about 1,632,982 (236)

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li   +11 more
wiley   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

open access: yesJournal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi   +15 more
wiley   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala   +6 more
wiley   +1 more source

Periodontitis and gastric disorders: Systematic review and meta‐analysis of functional dyspepsia and Helicobacter pylori gastritis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood   +3 more
wiley   +1 more source

Altered T cell immune profile and its prognostic implications in children with portal hypertension: A pilot study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Immune dysregulation in paediatric portal hypertension (PHT) is poorly understood. We aimed to characterise T cell phenotype and function and circulating immune mediators in children with PHT according to disease aetiology. Methods Forty‐four children with PHT (27 chronic liver disease [CLD]‐related and 17 portal vein thrombosis ...
Tengfei Si   +11 more
wiley   +1 more source

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