The Gut–Kidney Axis in Chronic Kidney Diseases [PDF]
DiagnosticsThe gut–kidney axis represents the complex interactions between the gut microbiota and kidney, which significantly impact the progression of chronic kidney disease (CKD) and overall patient health.
Kenji Tsuji +6 more
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Gut microbiota and gut-kidney axis in kidney diseases: therapeutic potential and perspectives of natural products [PDF]
Frontiers in PharmacologyGut microbiota exert core regulatory effects on systemic metabolic homeostasis and immune balance under physiological and pathological conditions. Marked gut dysbiosis occurs during the progression of chronic kidney disease (CKD), characterized by ...
Qianwei Wang +6 more
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The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis [PDF]
Animal Models and Experimental MedicineBackground The gut's impact on kidney health can be observed through its influence on the gut–kidney axis. However, using paraprobiotic and postbiotic agents may improve gut health and kidney function by affecting signaling pathways.
Fatemeh Haririzadeh Jouriani +6 more
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The role of mitochondria in the gut-kidney axis: implications for kidney health [PDF]
Frontiers in PharmacologyMitochondria, multifunctional organelles that regulate cellular energy metabolism and signaling pathways, play a pivotal role in maintaining the physiological functions of the gut and kidneys, as well as influencing the progression of chronic kidney ...
Qin Hu, Hua Jin, Hua Jin, Lan Hu, Xu Li
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The Intestinal Microbiota and Metabolites in the Gut-Kidney-Heart Axis of Chronic Kidney Disease
Frontiers in Pharmacology, 2022 Emerging evidences demonstrate the involvement of gut microbiota in the progression of chronic kidney disease (CKD) and CKD-associated complications including cardiovascular disease (CVD) and intestinal dysfunction.
Yinghui Huang +5 more
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ILC imbalance – a new piece in the gut-kidney axis puzzle [PDF]
Frontiers in ImmunologyBackgroundThe progression of chronic kidney disease (CKD) is closely linked to gut microbiota dysbiosis and the consequent accumulation of harmful microbial metabolites, forming a vicious cycle called “gut-kidney axis.” However, the specific immune ...
Xinyin Liu +4 more
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Bibliometric visualization analysis of gut-kidney axis from 2003 to 2022
Frontiers in Physiology, 2023 Background: The gut-kidney axis refers to the interaction between the gastrointestinal tract and the kidneys, and its disorders have become increasingly important in the development of kidney diseases.
Sinan Ai +10 more
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Precision targeting of gut-kidney axis: mucosal immunomodulation in IgA nephropathy—a perspective [PDF]
Frontiers in MedicineIgA nephropathy (IgAN) is a primary glomerular disease closely linked to mucosal immune dysregulation, involving a complex interplay between intestinal immune homeostasis and renal injury.
Li-hua Sun, Xia-xia Yang
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Targeting the gut‒kidney axis for lupus nephritis treatment: multimechanism regulatory strategies and evidence from Traditional Chinese medicine [PDF]
Chinese MedicineLupus nephritis (LN) treatment remains challenging because of the limited efficacy and substantial side effects of conventional immunosuppressive therapies.
Qingyun Fang +15 more
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Frontiers in MicrobiologyThe gut-brain-kidney axis represents a dynamic interplay among the gut microbiota, renal function, and neurological processes, emerging as a critical factor in chronic kidney disease (CKD) pathophysiology. This paper reviews recent data on the mechanisms
Jue Zhu +11 more
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