Results 31 to 40 of about 1,633,030 (251)
Review of gut-kidney crosstalk in acute kidney injury
Linchuang shenzangbing zazhi, 2021 With the characteristics of high incidence, high mortality, high health-economic cost and social burden, acute kidney injury（AKI）has become a worldwide public health problem.Currently there is no established pharmacotherapy for AKI.Emerging studies have ...
Hu Shou-ci, Ma Hong-zhen
doaj +1 more source
Nutritional Modulation of the Gut-Kidney Axis. [PDF]
NutrientsBackground: Chronic kidney disease (CKD) represents a state of persistent, sterile low-grade inflammation in which sustained innate immune activation accelerates renal decline and cardiovascular complications. Diet-induced gut dysbiosis and intestinal barrier dysfunction lower mucosal immune tolerance, promote metabolic endotoxemia, and position the ...
Bogdan RG +9 more
europepmc +3 more sources
The Gut-Kidney Axis and Effect on GFR. [PDF]
J Am Soc NephrolHanssen NMJ, van Raalte DH.
europepmc +4 more sources
Renal Sensing of Bacterial Metabolites in the Gut-kidney Axis [PDF]
Kidney360, 2021 Seminal works have now revealed the gut microbiota is connected with several diseases, including renal disorders. The balance between optimal and dysregulated host-microbiota interactions has completely changed our understanding of immunity and inflammation.
Orestes Foresto-Neto +2 more
openaire +2 more sources
Gut-kidney axis: Dysbiosis and renal disease. [PDF]
World J NephrolAccording United States renal data system the morbidity rate for chronic kidney disease (CKD) is 2.5 times than patients not affected by CKD and the mortality rate is 144.9 per 1000 persons-years. The gut microbiota is involved in uremic toxins (UTs) production.
Salvadori M, Rosso G.
europepmc +2 more sources
Microbiota-gut-kidney axis in health and renal disease. [PDF]
Int J Biol SciGut microbiota plays a central role in programming host metabolic function and immune modulation in both health and disease. Microbial dysbiosis leads to an increase in opportunistic pathogens and a reduction in beneficial bacteria, which collectively result in the excessive production of detrimental metabolites, particularly uremic toxins such as ...
Jin Y +5 more
europepmc +3 more sources
Hyperoxaluria: a gut–kidney axis? [PDF]
Kidney International, 2011 Hyperoxaluria leads to urinary calcium oxalate (CaOx) supersaturation, resulting in the formation and retention of CaOx crystals in renal tissue. CaOx crystals may contribute to the formation of diffuse renal calcifications (nephrocalcinosis) or stones (nephrolithiasis).
Robijn, Stef +4 more
openaire +3 more sources
Acta Pharmaceutica Sinica B, 2023 At present, clinical interventions for chronic kidney disease are very limited, and most patients rely on dialysis to sustain their lives for a long time.
Libin Pan +11 more
doaj +1 more source
The roles of gut microbiota and its metabolites in diabetic nephropathy
Frontiers in Microbiology, 2023 Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which increases the risk of renal failure and causes a high global disease burden.
Hui Zhao +7 more
doaj +1 more source
Derivation and elimination of uremic toxins from kidney-gut axis [PDF]
, 2023 Uremic toxins are chemicals, organic or inorganic, that accumulate in the body fluids of individuals with acute or chronic kidney disease and impaired renal function.
Ying Xu +7 more
core +1 more source