Results 51 to 60 of about 1,633,030 (251)
Targeting the Gut-Kidney Axis: Modulation of Gut Microbiota by Traditional Chinese Medicine for Chronic Kidney Disease Management. [PDF]
Toxins (Basel)The interaction between gut microbiota dysbiosis and CKD progression via the “gut–kidney axis” is increasingly recognized. Gut-derived uremic toxins (e.g., indoxyl sulfate and p-cresyl sulfate) accumulate systemically, while beneficial metabolites like ...
Xin Y, Pan L.
europepmc +2 more sources
The Gut-Kidney Axis: Putative Interconnections Between Gastrointestinal and Renal Disorders [PDF]
Frontiers in Endocrinology, 2018 Diabetic kidney disease (DKD) is a devastating condition associated with increased morbidity and premature mortality. The etiology of DKD is still largely unknown. However, the risk of DKD development and progression is most likely modulated by a combination of genetic and environmental factors.
Markku Lehto +6 more
openaire +3 more sources
Glomerulonephritis and inflammatory bowel disease: A tale of gut-kidney axis dysfunction
Autoimmunity Reviews, 2023 The incidence and prevalence of Inflammatory Bowel Disease (IBD) has increased over the past decades, imposing a growing socioeconomic burden on healthcare systems globally. Most of the morbidity and mortality related to IBD is typically attributed to gut inflammation and its complications; yet the disease is characterized by various extraintestinal ...
Doumas, S.A. +4 more
openaire +3 more sources
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis. [PDF]
, 2023 peer reviewedThe human body is colonized by at least the same number of microbial cells as it is composed of human cells, and most of these microorganisms are located in the gut.
WILMES, Paul +4 more
core +1 more source
Frontiers in MedicineMaintenance hemodialysis (MHD) has become the primary renal replacement therapy for patients with end-stage renal disease. The kidney-gut-brain axis represents a communication network connecting the kidney, intestine and brain.
Jie Yu +4 more
doaj +1 more source
Pediatric and adult point of view on the gut-kidney axis in CKD. [PDF]
Pediatr NephrolAbstract Chronic non-communicable diseases pose a significant global health challenge, with the human gut microbiota emerging as a key player in several (patho) physiological functions, including immunity, metabolic homeostasis, and inflammation.
Holle J, Behrens F, Koppe L.
europepmc +6 more sources
Gut–Kidney–Heart: A Novel Trilogy [PDF]
, 2023 The microbiota represents a key factor in determining health and disease. Its role in inflammation and immunological disorders is well known, but it is also involved in several complex conditions, ranging from neurological to psychiatric, from ...
Antonio Gasbarrini +10 more
core +2 more sources
Chronic kidney disease and gut microbiota
Heliyon, 2023 Chronic kidney disease (CKD) refers to a range of various pathophysiological processes correlated with abnormal renal function and a progressive loss in GFR. Just as dysbiosis and altered pathology of the gut are accompanied with hypertension, which is a
Siamak Amini Khiabani +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Gut Microbiota Dysbiosis in Diabetic Nephropathy: Mechanisms and Therapeutic Targeting via the Gut-Kidney Axis [PDF]
Frontiers in EndocrinologyXiaoran Wang
exaly +2 more sources