Results 91 to 100 of about 2,005,973 (405)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome

open access: yesScientific Reports, 2022
Complement activation plays a critical role in the pathogenesis of Guillain-Barré syndrome (GBS), a debilitating immune-mediated neuropathy. Mannose-binding lectin (MBL) is a complement activation factor of lectin pathway which as genetic host factor may
Israt Jahan   +8 more
doaj   +1 more source

Introduction to the human gut microbiota

open access: yesBiochemical Journal, 2017
The human gastrointestinal (GI) tract harbours a complex and dynamic population of microorganisms, the gut microbiota, which exert a marked influence on the host during homeostasis and disease.
E. Thursby, N. Juge
semanticscholar   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

open access: yes, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G   +5 more
core  

Immunodeficiency and the gut

open access: yesMedicine, 2003
Gastrointestinal diseases associated with impaired immunity are largely infectious, although an increased incidence of extranodal lymphoma is also found in the context of HIV infection. The range of such infections is related to the role of CD4-positive T cells in their eradication. Infections tend to occur with organisms of limited virulence and to be
openaire   +2 more sources

Ageing and the gut [PDF]

open access: yesProceedings of the Nutrition Society, 2012
The goal of this brief review is to address the role of the ageing gut in the genesis of malnutrition in the elderly. We assess the burden of malnutrition in the elderly, exploring the role of comorbid conditions and neurohumoral changes that take place to contribute towards the process of anorexia associated with ageing.
Britton, E., McLaughlin, J.T.
openaire   +2 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Trastornos de la interacción cerebro-intestino (trastornos funcionales digestivos): neuromoduladores en la práctica clínica (parte II)

open access: yesRevista Colombiana de Gastroenterología
Introducción: este artículo continúa la revisión de los neuromoduladores utilizados en la práctica clínica y su papel en el tratamiento de los diferentes trastornos de la interacción cerebro-intestino (TICI), en particular los gástricos, intestinales y ...
David Benigno Páramo Hernández   +4 more
doaj   +1 more source

TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]

open access: yes, 2019
The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen   +5 more
core   +2 more sources

Generalizing Minimal Supergravity [PDF]

open access: yesPhys.Lett.B692:121-125,2010, 2010
In Grand Unified Theories (GUTs), the Standard Model (SM) gauge couplings need not be unified at the GUT scale due to the high-dimensional operators. Considering gravity mediated supersymmetry breaking, we study for the first time the generic gauge coupling relations at the GUT scale, and the general gaugino mass relations which are valid from the GUT ...
arxiv   +1 more source

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