Results 91 to 100 of about 2,218,966 (387)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Trastornos de la interacción cerebro-intestino (trastornos funcionales digestivos): neuromoduladores en la práctica clínica (parte II)

Revista Colombiana de Gastroenterología
Introducción: este artículo continúa la revisión de los neuromoduladores utilizados en la práctica clínica y su papel en el tratamiento de los diferentes trastornos de la interacción cerebro-intestino (TICI), en particular los gástricos, intestinales y ...
David Benigno Páramo Hernández, Luis Fernando Pineda Ovalle, Laura Marcela Moya Valenzuela, Alejandro Concha Mejía, Juan David Páramo Díaz   +4 more
doaj   +1 more source

Elucidating the role of diet in maintaining gut health to reduce the risk of obesity, cardiovascular and other age-related inflammatory diseases: recent challenges and future recommendations

Gut microbes
A healthy balanced diet is crucial in protecting the immune system against infections and diseases. Poor diets, such as the Western diet, contribute to the development of metabolic diseases, hypertension, and obesity.
Tariq Aziz, N. Hussain, Zunaira Hameed, Lin Lin   +3 more
semanticscholar   +1 more source

SARS-CoV-2 productively infects human gut enterocytes

Science, 2020
Intestinal organoids as an infection model Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes an influenza-like disease with a respiratory transmission route; however, patients often present with gastrointestinal symptoms such as ...
M. Lamers, J. Beumer, J. van der Vaart, K. Knoops, Jens Puschhof, T. I. Breugem, R. Ravelli, J. P. Van Schayck, A. Mykytyn, H. Duimel, E. V. van Donselaar, Samra Riesebosch, H. Kuijpers, D. Schipper, Willine J. van de Wetering, Miranda de Graaf, M. Koopmans, E. Cuppen, P. Peters, B. Haagmans, H. Clevers   +20 more
semanticscholar   +1 more source

Ageing and the gut [PDF]

Proceedings of the Nutrition Society, 2012
The goal of this brief review is to address the role of the ageing gut in the genesis of malnutrition in the elderly. We assess the burden of malnutrition in the elderly, exploring the role of comorbid conditions and neurohumoral changes that take place to contribute towards the process of anorexia associated with ageing.
Britton, E., McLaughlin, J.T.
openaire   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Multidrug-resistant conjugative plasmid carrying mphA confers increased antimicrobial resistance in Shigella

Scientific Reports
Shigellosis remains a common gastrointestinal disease mostly in children 
Asaduzzaman Asad, Israt Jahan, Moriam Akter Munni, Ruma Begum, Morium Akter Mukta, Kazi Saif, Shah Nayeem Faruque, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos [PDF]

, 1991
We have used the vital dye, DiI, to analyze the contribution of sacral neural crest cells to the enteric nervous system in chick and mouse embryos. In order to label premigratory sacral neural crest cells selectively, DiI was injected into the lumen of ...
Bronner-Fraser, Marianne, Burgan, Scott, Fraser, Scott E., Serbedzija, George N.   +3 more
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Shift Work: Gut Health and Metabolic Disease [PDF]

, 2020
The number of people engaged in shift work continues to rise, and with it the research linking shift work to various diseases and conditions. Shift work changes the body’s sleeping patterns and circadian rhythms which has an effect on all parts of the ...
Lane, Hailey
core   +1 more source