Results 81 to 90 of about 979,913 (296)

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

Liver metastases in gastroenteropancreatic neuroendocrine tumours – treatment methods

Gastroenterology Review, 2020
Surgical approaches that allow the safe treatment of multiple, bilateral, large tumours, and that combine extirpative, ablative and interventional therapies, have expanded the population of patients with neuroendocrine tumors (NET) liver metastases (LMs)
Paweł Gut
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The role of probiotics in the treatment of endometriosis (ProMetrioS): a randomized double-blinded placebo-controlled cross-over trial

Trials
Background ProMetrioS is a randomized, blinded, placebo-controlled cross-over trial investigating the effect of a specific multispecies probiotic in patients with endometriosis.
Sara Kralj, Karlo Zeman, Mislav Mikuš, Andrija Karačić, Ana-Marija Liberati Pršo, Mario Ćorić, Ira Renko   +6 more
doaj   +1 more source

gut-4

, 2015
gut-
Mario Vallejo-Marin (3312780), Cooley, Arielle M., Buggs, Richard J. A., Arielle M. Cooley (3312777), Joshua R. Puzey (176857), Puzey, Joshua R., Vallejo-Marin, Mario, Richard J. A. Buggs (3285510)   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Gutted programs and children's guts [PDF]

Canadian Medical Association Journal, 2008
In polite parlance, it could be said educational administrators have now seen the error of their ways. After gutting physical education programs in the nation's schools a decade ago, they're now madly scrambling to revitalize previously robust physical education programs in the face of a ...
openaire   +1 more source