Results 61 to 70 of about 942,965 (287)
A note on compact and compact circular edge-colorings of graphs [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 Graphs and ...
Dariusz Dereniowski, Adam Nadolski
doaj +1 more source
Endocannabinoids in the Gut [PDF]
Cannabis and Cannabinoid Research, 2016 Cannabis has been used medicinally for centuries to treat a variety of disorders, including those associated with the gastrointestinal tract. The discovery of our bodies' own "cannabis-like molecules" and associated receptors and metabolic machinery - collectively called the endocannabinoid system - enabled investigations into the physiological ...
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Human transforming growth factor a (TGF-alpha) is digested to a smaller (1-43), less biologically active, form in acidic gastric juice [PDF]
, 2002 Publisher version: http://gut.bmj.com/content/51/6/787.full ...
Hansen, H +3 more
core +4 more sources
Revista Colombiana de GastroenterologíaIntroducción: en este artículo de revisión se desarrollan los principios básicos para el uso y los mecanismos de acción de los neuromoduladores utilizados en la práctica clínica y su papel en el tratamiento de los diferentes trastornos de la interacción
Luis Fernando Pineda Ovalle +4 more
doaj +1 more source
DEN Open, 2023 A 71‐year‐old obese woman was referred to our hospital with lower left abdominal pain. Computed tomography showed a 46 mm elliptic calcification lodged in the sigmoid‐descending colon junction (SDJ), which had been detected 5 years prior but was not ...
Tadataka Takagi +9 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Microbiology SpectrumLipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem +9 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source