Results 51 to 60 of about 979,913 (296)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Impact of Gut Microbiome on Gut Permeability in Liver and Gut Diseases

Microorganisms
Hepatobiliary and gastrointestinal conditions, including chronic liver diseases and inflammatory bowel disease, are associated with significant morbidity and mortality globally. While the pathophysiology and symptoms vary from one disease to another, aberrations of the gut microbiome with deleterious microbial products affecting the intestinal barrier ...
Punnag Saha, Phillipp Hartmann
openaire   +3 more sources

Taking it to the Gut [PDF]

BioTechniques, 2018
Sarah Webb examines how gastrointestinal organoids are transforming our understanding of biology and helping ...
openaire   +2 more sources

Preterm gut microbiota and metabolome following discharge from intensive care [PDF]

, 2015
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and ...
Skeath, Tom, Perry, J. D. (John), Nelson, Andrew, Stewart, Christopher, Marrs, Emma, Embleton, Nicholas, Fernstad, Sara J., Fernstad, Sara Johansson, Berrington, Janet, Marrs, E. C. L. (Emma), Cummings, Stephen, Perry, John, Skeath, Thomas   +12 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Molecular epidemiology of Campylobacter jejuni associated with Guillain–Barré syndrome

Scientific Reports
Campylobacter jejuni is the leading cause of bacterial gastroenteritis and its post-infectious sequelae, Guillain–Barré syndrome (GBS). Disease epidemiology of campylobacteriosis differs between high- and low-income countries.
Shoma Hayat, Md. Golam Mostafa, Md. Abu Jaher Nayeem, Ruma Begum, Ayesha Akter Anjuman, Saima Akhter Sadia, Imran Hasan, Asaduzzaman Asad, Zhahirul Islam   +8 more
doaj   +1 more source

The swine IsoLoop model of the gut host-microbiota interface enables intra-animal treatment comparisons to advance 3R principles [PDF]

Understanding gut-host microbiota interactions requires models that replicate human physiology while providing region-specific resolution, translational precision, and minimal animal use.
Muyyarikkandy, M.S., Nibbering, B., Law, A., Kuijper, E., Ramirez, A., Sponseller, B., Sauer, M., Scaria, J., Bayne, J., Opriessnig, T., Charavaryamath, C., Smits, W.K., Hu, Y., Mooyottu, S., Yousefi, F., Michael, A., Murphy, M., Hue, Yoonsung, Kujiper, E., Law, Andy, Kuijper, Ed, Murphy, Morgan, Michael, Alyona, Opriessnig, Tanja, Sauerk, Mary, Charavaryamathc, Chandrashekhar, Muyyarikkandy, Muhammed Shafeekh, Mooyottu, Shankumar, Sponsellern, Brett, Yousefie, Farnaz, Bayne, Jenna, Nibbering, Britt, Ramirez, Alejandro, Scarial, Joy, Smits, Wiep Klaas   +34 more
core   +1 more source

gut-community-microcosms

, 2022
Underlying data used to generate figures in Jin et al. 2022 "Microcosm cultures of a complex synthetic community reveal ecology and genetics of gut microbial organization". https://doi.org/10.1101/2022.09.13.507837.
Xiaofan Jin (10939167)
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source