Results 101 to 110 of about 2,005,973 (405)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Gut Microbiome, 2022 Metabolites produced by microbial fermentation in the human intestine, especially short-chain fatty acids (SCFAs), are known to play important roles in colonic and systemic health.
Maria LaBouyer +11 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Study of a Broadband Difference Interferometer Based on Low-Cost Polymer Slab Waveguides
Nanomaterials, 2019 A model and the waveguide parameters of a broadband, polymer-based slab waveguide difference interferometer is presented in this paper. The parameters were determined based on knowledge of the dispersion in the structure materials used to fabricate the ...
Kazimierz Gut
doaj +1 more source
Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]
, 2018 Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F. +3 more
core +1 more source
Employing nucleon decay as a fingerprint of SUSY GUT models using \texttt{SusyTCProton} [PDF]
, 2020 While the observation of nucleon decay would be a smoking gun of Grand Unified Theories (GUTs) in general, the ratios between the decay rates of the various channels carry rich information about the specific GUT model realization. To investigate this fingerprint of GUT models in the context of supersymmetric (SUSY) GUTs, we present the software tool ...
arxiv +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Scientific ReportsShigellosis remains a common gastrointestinal disease mostly in children
Asaduzzaman Asad +8 more
doaj +1 more source
Crosstalk between omega-6 oxylipins and the enteric nervous system: Implications for gut disorders?
Frontiers in Medicine, 2023 The enteric nervous system (ENS) continues to dazzle scientists with its ability to integrate signals, from the outside as well as from the host, to accurately regulate digestive functions.
Marine Mantel +4 more
doaj +1 more source
Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism
Gut microbes, 2016 The formation of SCFA is the result of a complex interplay between diet and the gut microbiota within the gut lumen environment. The discovery of receptors, across a range of cell and tissue types for which short chain fatty acids SCFA appear to be the ...
D. Morrison, T. Preston
semanticscholar +1 more source