Results 31 to 40 of about 2,005,973 (405)
The Microbiota-Gut-Brain Axis.
The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota (the trillions of microorganisms within and on our bodies) as one of the key regulators of gut ...
J. Cryan+32 more
semanticscholar +1 more source
Exploring the genetics of irritable bowel syndrome: A GWA study in the general population and replication in multinational case-control cohorts [PDF]
OBJECTIVE: IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
Agreus, Lars+43 more
core +1 more source
A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. [PDF]
Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly ...
Balskus, Emily P+8 more
core +1 more source
A human gut microbial gene catalogue established by metagenomic sequencing
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, assembly and characterization of 3.3 million non-redundant microbial ...
J. Qin+52 more
semanticscholar +1 more source
The Brain-Gut-Microbiome Axis. [PDF]
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir+3 more
core +2 more sources
Role of the gut microbiota in nutrition and health
Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and ...
Ana M Valdes+3 more
semanticscholar +1 more source
Regional and global changes in TCR [alpha][beta] T cell repertoires in the gut are dependent upon the complexity of the enteric microflora [PDF]
The repertoire of gut associated T cells is shaped by exposure to microbes, including the natural enteric microflora. Previous studies compared the repertoire of gut associated T cell populations in germ free (GF) and conventional mammals often focussing
Balk+46 more
core +1 more source
Baryogenesis, through the decays of heavy bosons, was considered to be one of the major successes of the grand unified theories (GUTs). It was then realized that the sphaleron processes erased any baryon asymmetry from the GUT-baryogenesis at a later stage.
arxiv +1 more source
Intro: Guillain-Barré syndrome (GBS), a life-threatening autoimmune disorder, triggered by an antecedent infection mostly by Campylobacter jejuni through molecular mimicry against host nerve gangliosides.
I. Jahan+9 more
doaj
Building GUTs from strings [PDF]
We study in detail the structure of Grand Unified Theories derived as the low-energy limit of orbifold four-dimensional strings. To this aim, new techniques for building level-two symmetric orbifold theories are presented. New classes of GUTs in the context of symmetric orbifolds are then constructed.
arxiv +1 more source