Results 41 to 50 of about 2,342,108 (381)

Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice

open access: yesScientific Reports, 2023
Alterations in intestinal mucin glycosylation have been associated with increased intestinal permeability and sensitivity to inflammation and infection. Here, we used mice lacking core 3-derived O-glycans (C3GnT−/−) to investigate the effect of impaired ...
Erika Coletto   +9 more
doaj   +1 more source

GUTs and Exceptional Branes in F-theory - II: Experimental Predictions [PDF]

open access: yes, 2009
We consider realizations of GUT models in F-theory. Adopting a bottom up approach, the assumption that the dynamics of the GUT model can in principle decouple from Planck scale physics leads to a surprisingly predictive framework.
Beasley, Chris   +2 more
core   +1 more source

Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

open access: yesGut, 2021
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and ...
Yun Kit Yeoh   +23 more
semanticscholar   +1 more source

TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]

open access: yes, 2019
The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen   +5 more
core   +2 more sources

The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome. [PDF]

open access: yes, 2016
Women with polycystic ovary syndrome (PCOS) have reproductive and metabolic abnormalities that result in an increased risk of infertility, diabetes and cardiovascular disease.
Kelley, Scott T   +3 more
core   +9 more sources

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

open access: yesAnimal Microbiome, 2019
Background Clostridium perfringens is a key pathogen in poultry-associated necrotic enteritis (NE). To date there are limited Whole Genome Sequencing based studies describing broiler-associated C. perfringens in healthy and diseased birds.
Raymond Kiu   +8 more
doaj   +1 more source

Higher total faecal short-chain fatty acid concentrations correlate with increasing proportions of butyrate and decreasing proportions of branched-chain fatty acids across multiple human studies

open access: yesGut Microbiome, 2022
Metabolites produced by microbial fermentation in the human intestine, especially short-chain fatty acids (SCFAs), are known to play important roles in colonic and systemic health.
Maria LaBouyer   +11 more
doaj   +1 more source

Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection. [PDF]

open access: yes, 2016
HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined.
Dandekar, Satya   +6 more
core   +1 more source

A core gut microbiome in obese and lean twins

open access: yesNature, 2008
The human distal gut harbours a vast ensemble of microbes (the microbiota) that provide important metabolic capabilities, including the ability to extract energy from otherwise indigestible dietary polysaccharides.
P. Turnbaugh   +14 more
semanticscholar   +1 more source

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

open access: yes, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ   +9 more
core   +2 more sources

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