Results 241 to 250 of about 172,085 (298)

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

Advanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey   +10 more
wiley   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

<i>Clostridium butyricum</i>-derived antimicrobial peptides remodel SCFA-producing gut symbionts to alleviate inflammation and enhance gut barrier integrity through microbial crosstalk. [PDF]

Curr Res Food Sci
Chen Y, Fu L, Li Y, Yang H, Wang C.
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

The Synergistic Role of Sargassum horneri Fucoidan and Lactobacillus plantarum: Microbiome and Gut Barrier Restoration in Zebrafish Colitis. [PDF]

Mar Drugs
Liyanage NM, Nagahawatta DP, Jayawardhana HHACK, Je JG, Yiqiao L, Yang F, Kim YS, Ko KY, Jeon YJ.   +8 more
europepmc   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Effects of Ultra-Processed Diets on Adiposity, Gut Barrier Integrity, Inflammation, and Microbiota in Male and Female Mice. [PDF]

Nutrients
Menezes C, Campolim CM, Triana A, Oliveira KM, Gama S Calixto L, Xavier FG, Saad MJA, Carneiro EM, Prada PO.   +8 more
europepmc   +1 more source

CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity. [PDF]

Sci Immunol
Gómez de Las Heras MM, Carrasco E, Pérez-Manrique M, Inohara N, Delgado-Pulido S, Fernández-Almeida Á, Gálvez-Castaño MI, Francos-Quijorna I, Simó C, García-Cañas V, Escrig-Larena JI, Aranda JF, Soto-Heredero G, Gabandé-Rodríguez E, Blanco EM, Días-Almeida J, Núñez G, Mittelbrunn M.   +17 more
europepmc   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics. [PDF]

Adv Sci (Weinh)
Chen W, Guo Q, Li H, Chi X, Ma X, Tang Y, Liang Q, Liu Z, Liu Y, Li J.   +9 more
europepmc   +1 more source

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV. [PDF]

Cell
Das Adhikari U, Froehle LM, Pipkin AN, Baharlou H, Linder AH, Shah P, Hussey A, Zhang Q, Nyquist S, Khwaled S, Chi F, Goswami S, Sedhain S, Hussain S, Diefenbach TJ, Read BJ, Kim B, Irvine D, Asowata O, Ladinsky M, Bjorkman P, Madela F, Kader S, Shalek AK, Ghebremichael M, Kloverpris H, Ringel AE, Yilmaz ÖH, Kwon DS.   +28 more
europepmc   +1 more source