Results 101 to 110 of about 59,952 (278)
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang +12 more
wiley +1 more source
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang +5 more
wiley +1 more source
Study on the effects of intestinal flora on gouty arthritis
Gouty arthritis (GA), a metabolic and immunologic disease, primarily affects joints. Dysbiosis of intestinal flora is an important cause of GA. The metabolic disorders of intestinal flora leading to GA and immune disorders might play an important role in
Niqin Xiao +9 more
doaj +1 more source
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu +10 more
wiley +1 more source
Changes in gut microbiota after gastric cancer surgery: a prospective longitudinal study
BackgroundThis study was designed to characterize gut microbiota changes of the patients with gastric cancer before and after the gastrectomy during their hospital staying periods.Methods16S ribosomal RNA (rRNA) gene sequencing was used to evaluate ...
Yuhua He +3 more
doaj +1 more source
INTESTINAL FLORA AFFECTS GUT-BRAIN AXIS
Extreme changes of the gut microbiota affect brain function and behaviour, as measured in animal models. A question arises as to the potential clinical relevance of these findings, especially when one considers the influence of dietary habits on the gut flora diversity.
openaire +2 more sources
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
Endometritis is a common reproductive disease in dairy cows, which can lead to low fertility or infertility and cause significant economic losses to the dairy farming industry.
Pan Liu +16 more
doaj +1 more source

