Results 101 to 110 of about 962,539 (314)

The interactions between traditional Chinese medicine and gut microbiota in cancers: Current status and future perspectives

open access: yesPharmacological Research
The gut microbiota, known as the “forgotten organ” and “human second genome,” comprises a complex microecosystem. It significantly influences the development of various tumors, including colorectal, liver, stomach, breast, and lung cancers, through both ...
Xuejiao Wei   +8 more
doaj   +1 more source

Summary of research advances on the correlation between chronic kidney disease and gastrointestinal microbiome

open access: yesLinchuang shenzangbing zazhi, 2021
The incidence of chronic kidney disease(CKD)in China has remained elevated and it shows an annually rising trend.However,no radical cure is not currently available.Exploring the risk factors of CKD is a research focus of nephrology.It is generally ...
Chen Li-hua   +3 more
doaj  

Corn Zein Nanocarriers for Agrochemical Delivery and Smart Packaging

open access: yesAdvanced Sustainable Systems, EarlyView.
This review explores zein, a corn‐derived biodegradable protein, as a multifunctional nanocarrier for sustainable agriculture and packaging. It examines advances in agrochemical delivery, smart packaging, and stimuli‐responsive systems, while addressing scalability, environmental fate, and regulatory barriers.
Muhammad Shahidul Islam   +2 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration

open access: yesNeural Regeneration Research
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision. Unfortunately, the specific pathogenesis remains unclear, and effective early treatment options are consequently lacking.
Qianzi Jin   +4 more
doaj   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

Systematic Analysis of the Association between Gut Flora and Obesity through High-Throughput Sequencing and Bioinformatics Approaches

open access: yesBioMed Research International, 2014
Eighty-one stool samples from Taiwanese were collected for analysis of the association between the gut flora and obesity. The supervised analysis showed that the most, abundant genera of bacteria in normal samples (from people with a body mass index (BMI)
Chih-Min Chiu   +10 more
semanticscholar   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

open access: yesAdvanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang   +4 more
wiley   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

open access: yesAdvanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang   +8 more
wiley   +1 more source

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