Results 111 to 120 of about 56,089 (298)

Intestinal Metabolism of Crocin and a Pharmacokinetics and Pharmacodynamics Study in the Chronic Social Defeat Stress Mouse Model

Pharmaceuticals
Orally administered crocin rapidly and efficiently rescues depressive-like behaviors in depression models; however, crocin levels in the circulatory and central nervous systems are rather low.
Fan Xiao, Yulong Song, Guangji Wang, Jiye Aa   +3 more
doaj   +1 more source

Ameliorative effects of pine nut peptide-zinc chelate (Korean pine) on a mouse model of Alzheimer's disease

Experimental Gerontology, 2023
In this study, 50 SD adult male mice were used to create an Alzheimer's disease model. The mice's learning and memory abilities were evaluated using an eight-arm radial maze experiment, and changes in body weight and food intake were noted.
Zhi Zhang, Jiajia Sun, Yanxia Li, Kexin Yang, Gang Wei, Shenglong Zhang   +5 more
doaj  

Gut microbiota nexus: Exploring the interactions with the brain, heart, lungs, and skin axes and their effects on health

Medicine in Microecology
It is becoming widely understood that gut microbiota and human health are related. It is now well-accepted that healthy gut flora plays a significant role in the host's overall health.
Pallab Chakraborty, Debolina Banerjee, Paramita Majumder, Joy Sarkar   +3 more
doaj  

Study on the effects of intestinal flora on gouty arthritis

Frontiers in Cellular and Infection Microbiology
Gouty arthritis (GA), a metabolic and immunologic disease, primarily affects joints. Dysbiosis of intestinal flora is an important cause of GA. The metabolic disorders of intestinal flora leading to GA and immune disorders might play an important role in
Niqin Xiao, Xiaoyu Zhang, Yujiang Xi, Zhenmin Li, Yuanyuan Wei, Jiayan Shen, Lin Wang, Dongdong Qin, Zhaohu Xie, Zhaofu Li   +9 more
doaj   +1 more source

Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis

Annals of Gastroenterological Surgery, EarlyView.
This study examined the effects of skeletal muscle mass on the short‐ and long‐term outcomes of rectal cancer. This study revealed that preoperative sarcopenia was associated with more total postoperative complications, more anastomotic leakage, and worse survival in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Kensuke Kaneko, Yuichiro Yokoyama, Hiroyuki Matsuzaki, Yuzo Nagai, Soichiro Ishihara   +9 more
wiley   +1 more source

MicroRNA‐433‐3p enhances chemosensitivity of glioma to cisplatin by downregulating NR5A2

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
miR‐433‐3p mediated the ability of NR5A2 to regulate the malignant behavior of glioma cells Abstract Objective We attempted to investigate influence of microRNA‐433‐3p on malignant progression of glioma and identify its molecular mechanism, thus laying groundwork for glioma management.
Jun Li, Jingshun Gu, Juntong Wang, Aiwu You, Yuyan Zhang, Guomin Rao, Shuang Li, Xuehua Ge, Kun Zhang, Dongchun Wang   +9 more
wiley   +1 more source

Changes in gut microbiota after gastric cancer surgery: a prospective longitudinal study

Frontiers in Oncology
BackgroundThis study was designed to characterize gut microbiota changes of the patients with gastric cancer before and after the gastrectomy during their hospital staying periods.Methods16S ribosomal RNA (rRNA) gene sequencing was used to evaluate ...
Yuhua He, Shilin Gao, Lili Jiang, Jie Yang   +3 more
doaj   +1 more source

Updated values of running quark and lepton masses at GUT scale in SM, 2HDM and MSSM [PDF]

Horizon, A Journal of Physics, Vol 2, 2013 (ISSN 2250-0871), 2012
Updated values of running quark and lepton masses at GUT (Grand unified theories) scales are important for fermion mass model building, and to calculate neutrino masses, in GUTs . We present their values at GUT scales, in SM, MSSM and 2HDM theories, using the latest values of running quark and lepton masses.
arxiv  

Light‐emitting diode irradiation targets aerobic glycolysis in cancer‐associated fibroblasts to inhibit metabolic coupling with colon cancer cells

Annals of Gastroenterological Surgery, EarlyView.
Blue LED irradiation targeted metabolic coupling between CAFs and colon cancer cells. Abstract Background The concepts examined in tumor metabolism research have been moving away from cancer cells themselves and the tumor microenvironment has become a focus of investigation.
Masaaki Nishi, Chiharu Nakasu, Toshiaki Yoshimoto, Takuya Tokunaga, T. Hideya Kashihara, Chie Takasu, Daichi Ishikawa, Yuma Wada, Mitsuo Shimada   +8 more
wiley   +1 more source

Central injection of abscisic acid attenuates mood disorders induced by subchronic stress in male mice

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function.
Mohammad Shabani, Hoda Ranjbar, Monavareh Soti, Reyhaneh Naderi   +3 more
wiley   +1 more source