Results 201 to 210 of about 59,952 (278)

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

Oral exposure to LaNiO₃ regulates the immune system, modulates gut flora, and induces intestinal autophagy in mice. [PDF]

Nanoscale Adv
Lin X, Zhang Y, Liu Q, Wu D, Zuo L, Zhang Y, Shi N, Chen R.   +7 more
europepmc   +1 more source

Why we age

Biological Reviews, EarlyView.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

Integrative network pharmacology, metabolomics and gut flora studies reveal mechanisms of action of <i>Rhododendron molle</i> (Blume) G. Don to ameliorate liver injury. [PDF]

Front Microbiol
Jiang X, Zhuang Y, Meng T, Meng T, Li X, He D, Meng H, Chang H.   +7 more
europepmc   +1 more source

The spread of non‐native species

Biological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock, Ali Serhan Tarkan, Irene Martín‐Forés, Stelios Katsanevakis, Ronaldo Sousa, Ismael Soto, Andy J. Green, Antonín Kouba, Teun Everts, Victoria Dominguez Almela, Nadège Belouard, Cang Hui, Jamie Bojko, Victor Deklerck, Margaux Boeraeve, Franz Essl, J. Robert Britton   +16 more
wiley   +1 more source

Additional file 1 of Putative causal relations among gut flora, serums metabolites and arrhythmia: a Mendelian randomization study

Kaiyuan Li, Peng Liu, Miao Liu, Jun Ye, Li Zhu   +4 more
openalex   +1 more source

Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates

Biological Reviews, EarlyView.
ABSTRACT Oropharyngeal food processing exhibits a remarkable diversity among vertebrates, reflecting the evolution of specialised ‘processing centres’ associated with the mandibular, hyoid, and branchial arches. Although studies have detailed various food‐processing strategies and mechanisms across vertebrates, a coherent and comprehensive terminology ...
Daniel Schwarz, Maja Mielke, Stephan Handschuh, Anthony Herrel, Patrick Lemell, Léa Da Cunha, Nicolai Konow   +6 more
wiley   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

[<i>Poria cocos</i> polysaccharide alleviates cyclophosphamide-induced intestinal barrier dysfunction and inflammation in mice by modulating gut flora]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang Y, Duan Y, Zhang C, Yu L, Liu Y, Xing L, Wang L, Yu N, Peng D, Chen W, Wang Y.   +10 more
europepmc   +1 more source

Gut flora specific immune responses in multiple sclerosis

, 2014
Elena Piras, Viviana Annibali, Marco De Bardi, Claudio Gasperini, Stefano Ruggieri, Maurizio Centonze, Giovanni Ristori, Ristori, G., Lisa Rizzetto, Duccio Cavalieri, Carlotta De Filippo, Daniela F. Angelini, Luca Battistini, De Filippo, Carlotta   +13 more
openalex   +1 more source