Results 231 to 240 of about 892,774 (277)

A head start: The relationship of placental factors to craniofacial and brain development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver   +2 more
wiley   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming   +14 more
wiley   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling   +9 more
wiley   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito   +9 more
wiley   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source
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Gut flora in health and disease

The Lancet, 2003
The human gut is the natural habitat for a large and dynamic bacterial community, but a substantial part of these bacterial populations are still to be described. However, the relevance and effect of resident bacteria on a host's physiology and pathology has been well documented.
Francisco Guarner, Juan-R. Malagelada
semanticscholar   +6 more sources

Altered gut Flora in uremia [PDF]

open access: possibleJournal of Renal Nutrition, 1996
The objective of this review is to show the influence of altered gut flora in patients with chronic renal failure (CRF). This flora produces toxic metabolites that can be reduced by a biological intervention that acts through modification of bacterial overgrowth in the small intestine.
Stephen R. Dunn, Michael L. Simenhoff
openaire   +1 more source

Overview of gut flora and probiotics

International Journal of Food Microbiology, 1998
Scientific developments in recent years have opened new frontiers and enable a better understanding of the gastrointestinal tract (GIT) as a complex and delicately balanced ecosystem. This paper focuses on more recent information related to the microbial population of the GIT and its functional role in human physiology and health.
Holzapfel, Wilhelm Heinrich   +4 more
openaire   +3 more sources

Obesity and gut flora

Nature, 2006
The intestinal bacteria in obese humans and mice differ from those in lean individuals. Are these bacteria involved in how we regulate body weight, and are they a factor in the obesity epidemic?
Randy J. Seeley, Matej Bajzer
openaire   +2 more sources

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