Results 241 to 250 of about 67,590 (294)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

open access: yesExploration, EarlyView.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang   +7 more
wiley   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

open access: yesExploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen   +8 more
wiley   +1 more source

Elimination of Fusobacterium nucleatum With Biomimetic Nanoparticles to Reverse Tumor Immunosuppression and Enhance Colorectal Cancer Therapy

open access: yesExploration, EarlyView.
Tumor‐related pathogenic bacteria can affect the treatment efficiency of tumors. Therefore, we have designed a nanoparticle that can accurately target tumor cells and related pathogenic bacteria, reverse the immunosuppressive effect of pathogenic bacteria on tumors, and synergistically enhance tumor treatment efficiency through sonodynamic therapy ...
Mengting Zhou   +10 more
wiley   +1 more source
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Gut flora in health and disease

Lancet, The, 2003
The human gut is the natural habitat for a large and dynamic bacterial community, but a substantial part of these bacterial populations are still to be described. However, the relevance and effect of resident bacteria on a host's physiology and pathology has been well documented.
FRANCISCO Guarner, Juan-R Malagelada
exaly   +6 more sources

The metabolism of drugs by the gut flora

European Journal of Drug Metabolism and Pharmacokinetics, 1994
Gut flora and gut contents can be considered as a system with huge metabolic capacity, qualitatively and quantitatively different from the body cells and organs. That system changes along with life and nutrition, but despite broad investigation has not yet been defined satisfactorily.
Momir Mikov, Mikov M
exaly   +3 more sources

Overview of gut flora and probiotics

International Journal of Food Microbiology, 1998
Scientific developments in recent years have opened new frontiers and enable a better understanding of the gastrointestinal tract (GIT) as a complex and delicately balanced ecosystem. This paper focuses on more recent information related to the microbial population of the GIT and its functional role in human physiology and health.
Holzapfel, Wilhelm Heinrich   +4 more
openaire   +2 more sources

Role of gut flora in the genotoxicity of dinitrotoluene

Nature, 1982
Dinitrotoluene (DNT), an important industrial nitroaromatic compound, is a potent hepatocarcinogen in rats. Male Fischer-334 rats fed technical-grade DNT in the diet for 12 months showed a 100% incidence of hepatocellular carcinomas1. However, various in vitro and in vivo short-term tests using several genotoxic end points have failed to show activity ...
J C, Mirsalis   +3 more
openaire   +2 more sources

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