Results 251 to 260 of about 892,774 (277)

Digoxin Inactivation by the Gut Flora in Infancy and Childhood

Pediatrics, 1987
Inactivation of digoxin by reduction of the lactone ring has recently been shown to occur in one third of adults and to be mediated by anaerobic intestinal bacteria. Children from birth through adolescence were studied to determine the pattern of development of this gut flora-mediated process.
John Lindenbaum, Vincent P. Butler, Jay F. Dobkin, Jnan R. Saha, Timothy C. Wang, Linda Linday   +5 more
openaire   +2 more sources

Gut flora and metabolism are altered in epilepsy and partially restored after ketogenic diets.

Microbial Pathogenesis, 2021
Xue Gong, Qianyun Cai, Xu Liu, D. An, Dong Zhou, R. Luo, Rong Peng, Z. Hong   +7 more
semanticscholar   +1 more source

Review article: metronidazole and the anaerobic gut flora

Alimentary Pharmacology & Therapeutics, 1990
SUMMARYMetronidazole is a nitro‐imidazole drug which was discovered nearly 30 years ago. Metronidazole has remained the mainstay of anti‐anaerobic therapy following a chance observation that its activity included anaerobic organisms. The predominant human reservoir of these anaerobic organisms is the gastrointestinal tract.
J. W. Stone, T. S. J. Elliott
openaire   +3 more sources

Therapeutic Manipulation of Gut Flora

Science, 2000
In developed countries as many as two individuals in every thousand suffer from inflammatory bowel disease (ulcerative colitis and Crohn's disease). In his Perspective, Shanahan discusses a new therapeutic approach to treating these conditions in which bacteria normally found in the gut are engineered to produce the anti-inflammatory cytokine ...
openaire   +2 more sources

Gut Flora and the Irritable Bowel Syndrome

The American Journal of Gastroenterology, 2004
TO THE EDITOR: In a recent issue, Pimentel et al. (1) reported a double-blind, randomized, placebo-controlled study in which normalization of the lactulose breath hydrogen test (LBHT) following antibiotic treatment was found to correlate with symptom improvement in patients with irritable bowel syndrome (IBS).
Stephen M. Riordan, Jelica Kurtovic
openaire   +2 more sources

Gut flora and disease resistance

1992
It is now recognized that the indigenous microflora of humans and animals provides protection against infections with pathogenic microorganisms. Evidence of a protective role for the intestinal flora was obtained largely from studies with either germ-free or antibiotic-treated experimental animals that are much more susceptible to infections with ...
openaire   +2 more sources

Immune effects of the normal gut flora

Monatsschrift Kinderheilkunde, 1998
Die Darmflora ist fur eine normale Entwicklung des menschlichen Immunsystems notwendig, und zwar sowohl in bezug auf seine Fahigkeit, mit Abwehr zu antworten, als auch seine Fahigkeit, immunologische Toleranz zu entwickeln, hauptsachlich via Darmmukosa, d.h. orale Toleranz.
openaire   +2 more sources

The modulatory effect of plant polysaccharides on gut flora and the implication for neurodegenerative diseases from the perspective of the microbiota-gut-brain axis.

International Journal of Biological Macromolecules, 2020
Qiaoyu Sun, Lu Cheng, Xiaoxiong Zeng, Xin Zhang, Zufang Wu, P. Weng   +5 more
semanticscholar   +1 more source

[Multiple Sclerosis and Commensal Gut Flora].

Brain and nerve = Shinkei kenkyu no shinpo, 2016
Although a symbiotic relationship between commensal gut microbiota and host is widely appreciated, recent works have indicated that normal gut flora functions to prevent inflammatory bowel diseases and obesity in the host, indicating a more mutualistic relationship. Dysbiosis of the commensal flora may lead to development of these disorders.
openaire   +3 more sources

Ecology of gut flora

The American Journal of Clinical Nutrition, 1973
openaire   +2 more sources