Results 1 to 10 of about 113,380 (310)

Gut Microbes and Eye Disease [PDF]

Ophthalmic Research, 2021
Microbial symbionts in the gut are increasingly recognized as having important effects on health and disease, but have only recently begun to be linked to diseases of the eye. We review current research on the intestinal microbiota’s relationship to ocular disease, focusing on autoimmune uveitis, diabetic retinopathy, age-related macular degeneration ...
Patrick Donabedian, Elizabeth Dawson, Qiuhong Li, Jinghua Chen   +3 more
openaire   +2 more sources

Gut microbes and health

Gastroenterología y Hepatología (English Edition), 2021
The human body is populated by myriads of microorganisms throughout its surface and in the cavities connected to the outside. The microbial colonisers of the intestine (microbiota) are a functional and non-expendable part of the human organism: they provide genes (microbiome) and additional functions to the resources of our species and participate in ...
Álvarez, Julia, Fernández Real, José Manuel, Guarner, Francisco, Gueimonde, Miguel, Rodríguez, Juan Miguel, Saenz de Pipaon, Miguel, Sanz, Yolanda   +6 more
openaire   +3 more sources

An optimised protocol for detection of SARS-CoV-2 in stool

BMC Microbiology, 2021
Background SARS-CoV-2 has been detected in stool samples of COVID-19 patients, with potential implications for faecal-oral transmission. Compared to nasopharyngeal swab samples, the complexity of the stool matrix poses a challenge in the detection of the
Tianqi Li, Enriqueta Garcia-Gutierrez, Daniel A. Yara, Jacob Scadden, Jade Davies, Chloe Hutchins, Alp Aydin, Justin O’Grady, Arjan Narbad, Stefano Romano, Lizbeth Sayavedra   +10 more
doaj   +1 more source

Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

Frontiers in Aging Neuroscience, 2022
Age-associated changes in the structure of the intestinal microbiome and in its interaction with the brain via the gut-brain axis are increasingly being implicated in neurological and neurodegenerative diseases.
Aimée Parker, Steve A. James, Catherine Purse, Arlaine Brion, Andrew Goldson, Andrea Telatin, David Baker, Simon R. Carding   +7 more
doaj   +1 more source

The Pregnancy and EARly Life study (PEARL) - a longitudinal study to understand how gut microbes contribute to maintaining health during pregnancy and early life

BMC Pediatrics, 2021
Background The early life period represents the first step in establishing a beneficial microbial ecosystem, which in turn affects both short and longer-term health.
Sarah Phillips, Rachel Watt, Thomas Atkinson, George M Savva, Antonietta Hayhoe, Lindsay J Hall, on behalf of the PEARL study team   +6 more
doaj   +1 more source

Extracellular vesicles produced by the human gut commensal bacterium Bacteroides thetaiotaomicron elicit anti-inflammatory responses from innate immune cells

Frontiers in Microbiology, 2022
Bacterial extracellular vesicles (BEVs) produced by gut commensal bacteria have been proposed to play an important role in maintaining host homeostasis via interactions with the immune system.
Sonia Fonseca, Ana L. Carvalho, Ana L. Carvalho, Ariadna Miquel-Clopés, Emily J. Jones, Rokas Juodeikis, Régis Stentz, Simon R. Carding, Simon R. Carding   +8 more
doaj   +1 more source

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

Microbiome, 2022
Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias.
Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding   +14 more
doaj   +1 more source

LotuS2: an ultrafast and highly accurate tool for amplicon sequencing analysis

Microbiome, 2022
Background Amplicon sequencing is an established and cost-efficient method for profiling microbiomes. However, many available tools to process this data require both bioinformatics skills and high computational power to process big datasets. Furthermore,
Ezgi Özkurt, Joachim Fritscher, Nicola Soranzo, Duncan Y. K. Ng, Robert P. Davey, Mohammad Bahram, Falk Hildebrand   +6 more
doaj   +1 more source

First Foods and Gut Microbes [PDF]

Frontiers in Microbiology, 2017
The establishment of the human gut microbiota in early life has been associated with later health and disease. During the 1st months after birth, the microbial composition in the gut is known to be affected by the mode of delivery, use of antibiotics, geographical location and type of feeding (breast/formula).
Laursen, Martin Frederik, Bahl, Martin I, Michaelsen, Kim F., Licht, Tine R   +3 more
openaire   +5 more sources

Evolution of Mammals and Their Gut Microbes [PDF]

Science, 2008
Mammals are metagenomic in that they are composed of not only their own gene complements but also those of all of their associated microbes. To understand the coevolution of the mammals and their indigenous microbial communities, we conducted a network-based analysis of bacterial 16 S ...
Ley, R. ; https://orcid.org/0000-0002-9087-1672, Hamady, M., Lozupone, C., Turnbaugh, P., Ramey, R., Bircher, J., Schlegel, M., Tucker, T., Schrenzel, M., Knight, R., Gordon, J.   +10 more
openaire   +3 more sources