Results 11 to 20 of about 113,380 (310)

Microbiota-derived metabolites as drivers of gut-brain communication [PDF]

, 2022
Alterations in the gut microbiota composition have been associated with a range of neurodevelopmental, neurodegenerative, and neuropsychiatric disorders.
Koistinen Ville, Leyrolle Quentin, Layé Sophie, Kärkkäinen Olli, Ahmed Hany, Delzenne Nathalie, Hanhineva Kati   +6 more
core   +3 more sources

Genome-scale metabolic modelling of human gut microbes to inform rational community design. [PDF]

Gut Microbes
Data availability: All data generated or analyzed during this study are included in this published article and its supplementary information files.
Molina Ortiz JP, McClure DD, Holmes A, Rice SA, Read MN, Shanahan ER.   +5 more
europepmc   +2 more sources

Comparison of PCR versus PCR-Free DNA Library Preparation for Characterising the Human Faecal Virome

Viruses, 2021
The human intestinal microbiota is abundant in viruses, comprising mainly bacteriophages, occasionally outnumbering bacteria 10:1 and is termed the virome.
Shen-Yuan Hsieh, Mohammad A. Tariq, Andrea Telatin, Rebecca Ansorge, Evelien M. Adriaenssens, George M. Savva, Catherine Booth, Tom Wileman, Lesley Hoyles, Simon R. Carding   +9 more
doaj   +1 more source

Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice

Scientific Reports, 2023
Alterations in intestinal mucin glycosylation have been associated with increased intestinal permeability and sensitivity to inflammation and infection. Here, we used mice lacking core 3-derived O-glycans (C3GnT−/−) to investigate the effect of impaired ...
Erika Coletto, George M. Savva, Dimitrios Latousakis, Matthew Pontifex, Emmanuelle H. Crost, Laura Vaux, Andrea Telatin, Kirk Bergstrom, David Vauzour, Nathalie Juge   +9 more
doaj   +1 more source

The Cynomolgus Macaque Intestinal Mycobiome Is Dominated by the Kazachstania Genus and K. pintolopesii Species

Journal of Fungi, 2022
The cynomolgus macaque, Macaca fascicularis, is a non-human primate (NHP) widely used in biomedical research as its genetics, immunology and physiology are similar to those of humans.
Steve A. James, Aimee Parker, Catherine Purse, Andrea Telatin, David Baker, Sandy Holmes, James Durham, Simon G. P. Funnell, Simon R. Carding   +8 more
doaj   +1 more source

Much ado about nothing? Off-target amplification can lead to false-positive bacterial brain microbiome detection in healthy and Parkinson’s disease individuals

Microbiome, 2021
Background Recent studies suggested the existence of (poly-)microbial infections in human brains. These have been described either as putative pathogens linked to the neuro-inflammatory changes seen in Parkinson’s disease (PD) and Alzheimer’s disease (AD)
Janis R. Bedarf, Naiara Beraza, Hassan Khazneh, Ezgi Özkurt, David Baker, Valeri Borger, Ullrich Wüllner, Falk Hildebrand   +7 more
doaj   +1 more source

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection

Disease Models & Mechanisms, 2022
The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath, Edgaras Laveckis, Andrew Bell, Emmanuelle Crost, Nathalie Juge, Stephanie Schüller   +5 more
doaj   +1 more source

Genomic analysis of a rare recurrent Listeria monocytogenes prosthetic joint infection indicates a protected niche within biofilm on prosthetic materials

Scientific Reports, 2021
Listeria monocytogenes is a rare cause of prosthetic joint infections (PJI). In this study, we describe a case of recurrent L. monocytogenes infections, 39 months apart, following debridement and retention of a prosthetic hip.
Chloe Hutchins, Lizbeth Sayavedra, Maria Diaz, Puja Gupta, Elizabeth Tissingh, Chiamaka Elumogo, John Nolan, Ian Charles, Ngozi Elumogo, Arjan Narbad   +9 more
doaj   +1 more source

Gut-Brain Communication is Influenced by Gut Microbes [PDF]

Indian Journal of Microbiology, 2011
Mammalian brain is of particular interest to us and is susceptible to environmental influences during perinatal life. A recent study by a group of researchers at Stockholm Brain Institute and Genome Institute of Singapore revealed that the gut bacteria influence brain development and behaviour [1].
Vatsala, Dwivedi, Rup, Lal
openaire   +2 more sources

and their various contributions to gut health [PDF]

, 2020
Over the last two decades our understanding of the gut microbiota and its contribution to health and disease has been transformed. Among a new ‘generation’ of potentially beneficial microbes to have been recognized are members of the genus Eubacterium ...
R. Paul Ross, Mukherjee, Arghya, Cotter, Paul D., Ross, R. Paul, Paul D. Cotter, Arghya Mukherjee, Cathy Lordan, Lordan, Cathy   +7 more
core   +1 more source