Results 1 to 10 of about 260,831 (351)

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Extrachromosomal circular DNA as a novel biomarker for the progression of colorectal cancer

Molecular Medicine
Background Extrachromosomal circular DNA (eccDNA) has potential in tumor diagnosis, particularly for improving diagnostic accuracy and early cancer detection; however, many challenges remain in its application to clinical practice. Methods We conducted a
Quanpeng Qiu, Yi Ding, Xiaolong Guo, Jing Han, Jiaqi Zhang, Yaping Liu, Junjun She, Yinnan Chen   +7 more
doaj   +1 more source

Gut microbiome in modulating immune checkpoint inhibitors

EBioMedicine, 2022
Summary: Gut microbiome has been increasingly recognized for its influence on a diverse array of human diseases including cancer, and may also influence the outcome of cancer therapies.
Xiang Li, Shaoqiang Zhang, Gang Guo, Jing Han, Jun Yu   +4 more
doaj  

Disordered development of gut microbiome interferes with the establishment of the gut ecosystem during early childhood with atopic dermatitis

Gut Microbes, 2022
The gut microbiome influences the development of allergic diseases during early childhood. However, there is a lack of comprehensive understanding of microbiome-host crosstalk. Here, we analyzed the influence of gut microbiome dynamics in early childhood
Min-Jung Lee, Yoon Mee Park, Byunghyun Kim, in Hwan Tae, Nam-Eun Kim, Marina Pranata, Taewon Kim, Sungho Won, Nam Joo Kang, Yun Kyung Lee, Dong-Woo Lee, Myung Hee Nam, Soo-Jong Hong, Bong-Soo Kim   +13 more
doaj   +1 more source

Acidification increases abundances of Vibrionales and Planctomycetia associated to a seaweed-grazer system: potential consequences for disease and prey digestion efficiency [PDF]

, 2018
Ocean acidification significantly affects marine organisms in several ways, with complex interactions. Seaweeds might benefit from rising CO2 through increased photosynthesis and carbon acquisition, with subsequent higher growth rates.
Aires, Aires, Aires, Asnaghi, Asplund, Avelin Mary, Barbieri, Barneah, Beleneva, Bengtsson, Berg, Bodelier, Bodenhausen, Bourne, Bourne, Branch, Briggs, Burgess, Burke, Burke, Caporaso, Cardoso, Case, Cayrou, Chao, Chojnacka, Church, Clarke, Clarke, Cornwall, Cottrell, Currie, Davis, Devine, Dimitrieva, Dittmer, Dudek, Eberl, Edgar, Egan, Fabry, Fenchel, Fraune, Frey, Fuerst, Gachon, Garrity, Glöckner, Goffredi, Greiman, Gutow, Hacquard, Harley, Hassenrück, Head, Hentschel, Hollants, Holmstrom, Holmström, Hong, Huggett, Kerfahi, King, Kirchman, Koch, Kooperman, Kroeker, Lachnit, Lage, Lane, Liu, Longford, Mackie, Maki, Marzinelli, Matsuo, Matsuo, Mattila, McDonald, Mensch, Meron, Meusnier, Meziti, Moisander, Morrow, Nedashkovskaya, Olischläger, Parris, Patel, Perlman, Poore, Porzio, Sawabe, Schulze, Shah, Shnit-Orland, Simon, Singh, Singh, Song, Staufenberger, Sullam, Sunagawa, Suzuki, Taylor, Thomas, Thomas, Thurber, Tietjen, Tujula, Urabe, Van De Waal, Vezzulli, Vieira, Wang, Wang, Wang, Webster, Witt, Yuksel, Zimmer, Zimmer, Zimmer   +122 more
core   +3 more sources

Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels [PDF]

, 2020
Background Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects millions of people worldwide.
Alam, Mohammad T., Amos, Gregory C. A., Arasaradnam, Ramesh P., Murch, Simon, Murphy, Andrew, Wellington, E. M. H.   +5 more
core   +1 more source

The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Scientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng   +10 more
doaj   +1 more source

The Role of Gut Dysbiosis in the Loss of Intestinal Immune Cell Functions and Viral Pathogenesis

Microorganisms, 2023
The gut microbiome plays a critical role in maintaining overall health and immune function. However, dysbiosis, an imbalance in microbiome composition, can have profound effects on various aspects of human health, including susceptibility to viral ...
Farzaneh Fakharian, Siva Thirugnanam, David A. Welsh, Woong-Ki Kim, Jay Rappaport, Kyle Bittinger, Namita Rout   +6 more
doaj   +1 more source

Gut Microbes and the Brain: Paradigm Shift in Neuroscience [PDF]

, 2014
The discovery of the size and complexity of the human microbiome has resulted in an ongoing reevaluation of many concepts of health and disease, including diseases affecting the CNS. A growing body of preclinical literature has demonstrated bidirectional
Cryan, John F., Knight, Rob, Mayer, Emeran A., Mazmanian, Sarkis K., Tillisch, Kirsten   +4 more
core   +1 more source

Emerging Evidence of the Gut Microbiome in Chemotherapy: A Clinical Review

Frontiers in Oncology, 2021
Increasing evidence suggests that the gut microbiome is associated with both cancer chemotherapy (CTX) outcomes and adverse events (AEs). This review examines the relationship between the gut microbiome and CTX as well as the impact of CTX on the gut ...
Byeongsang Oh, Byeongsang Oh, Byeongsang Oh, Byeongsang Oh, Frances Boyle, Frances Boyle, Nick Pavlakis, Nick Pavlakis, Stephen Clarke, Stephen Clarke, Alex Guminski, Alex Guminski, Alex Guminski, Thomas Eade, Thomas Eade, Thomas Eade, Gillian Lamoury, Gillian Lamoury, Gillian Lamoury, Susan Carroll, Susan Carroll, Susan Carroll, Marita Morgia, Marita Morgia, Andrew Kneebone, Andrew Kneebone, Andrew Kneebone, George Hruby, George Hruby, George Hruby, Mark Stevens, Mark Stevens, Wen Liu, Brian Corless, Mark Molloy, Towia Libermann, Towia Libermann, David Rosenthal, Michael Back, Michael Back, Michael Back   +40 more
doaj   +1 more source