Results 101 to 110 of about 260,831 (351)
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
The Human Microbiome and Recurrent Abdominal Pain in Children [PDF]
, 2010 This project explores the nature of the human intestinal microbiome in healthy children and children with recurrent abdominal pain. The overall goal is to obtain a robust knowledge base of the intestinal microbiome in children without evidence of pain or
Debasmita Mandal +12 more
core +3 more sources
Advanced Science, EarlyView.This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu +16 more
wiley +1 more source
The role of host traits and geography in shaping the gut microbiome of insectivorous bats
mSphereThe gut microbiome is a symbiotic microbial community associated with the host and plays multiple important roles in host physiology, nutrition, and health.
Wentao Dai +9 more
doaj +1 more source
The gut microbiome: Relationships with disease and opportunities for therapy. [PDF]
, 2019 Over the past decade, our view of human-associated microbes has expanded beyond that of a few species toward an appreciation of the diverse and niche-specialized microbial communities that develop in the human host with chronological age.
Durack, Juliana, Lynch, Susan V
core
Advanced Science, EarlyView.In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang +10 more
wiley +1 more source
Correlations of Host Genetics and Gut Microbiome Composition [PDF]
, 2016 The human gut microbiome has a considerable impact on host health. The long list of microbiome-related health disorders raises the question of what in fact determines microbiome composition.
Krystyna Dąbrowska, Wojciech Witkiewicz
core +1 more source
Alterations of the Gut Microbiome in Hypertension [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Introduction: Human gut microbiota is believed to be directly or indirectly involved in cardiovascular diseases and hypertension. However, the identification and functional status of the hypertension-related gut microbe(s) have not yet been surveyed in a comprehensive manner.
Qiulong Yan +19 more
openaire +4 more sources
Advanced Science, EarlyView.Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang +11 more
wiley +1 more source
The Gut Microbiome in Neuromyelitis Optica [PDF]
Neurotherapeutics, 2018 Neuromyelitis optica (NMO) is a rare, disabling, sometimes fatal central nervous system inflammatory demyelinating disease that is associated with antibodies ("NMO IgG") that target the water channel protein aquaporin-4 (AQP4) expressed on astrocytes. There is considerable interest in identifying environmental triggers that may elicit production of NMO
Zamvil, Scott S +3 more
openaire +5 more sources