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Gut Microbiome Toxicity: Connecting the Environment and Gut Microbiome-Associated Diseases [PDF]
The human gut microbiome can be easily disturbed upon exposure to a range of toxic environmental agents. Environmentally induced perturbation in the gut microbiome is strongly associated with human disease risk. Functional gut microbiome alterations that
Pengcheng Tu+8 more
doaj +4 more sources
The gut microbiome in konzo [PDF]
AbstractKonzo, a distinct upper motor neuron disease associated with a cyanogenic diet and chronic malnutrition, predominately affects children and women of childbearing age in sub-Saharan Africa. While the exact biological mechanisms that cause this disease have largely remained elusive, host-genetics and environmental components such as the gut ...
Daniel Okitundu+22 more
openaire +6 more sources
Gut Microbiome and Osteoporosis [PDF]
Gut microbiome refers to the microbes that live in human digestive tract and are symbiotic with the human body. They participate in the regulation of various physiological and pathological processes of the human body and are associated with various diseases. The pathological process of osteoporosis is affected by gut microbes.
Wenge Ding, Fei Hua, Kai Ding
openaire +5 more sources
Marsupial Gut Microbiome [PDF]
The study of the gut microbiome in threatened wildlife species has enormous potential to improve conservation efforts and gain insights into host-microbe coevolution. Threatened species are often housed in captivity, and during this process undergo considerable changes to their gut microbiome.
Chong, Rowena+3 more
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Enterotypes of the human gut microbiome [PDF]
Our knowledge of species and functional composition of the human gut microbiome is rapidly increasing, but it is still based on very few cohorts and little is known about variation across the world. By combining 22 newly sequenced faecal metagenomes of individuals from four countries with previously published data sets, here we identify three robust ...
Manimozhiyan Arumugam+42 more
semanticscholar +8 more sources
Studies about the gut microbiota in CKD patients have shown presence of dysbiosis, which is related to complications like inflammation and oxidative stress, important risk factors to cardiovascular disease. Diet is the first modulator of gut microbiota and, researchers have studied some strategies to reduce the dysbiosis in CKD patients such as ...
Denise Mafra, Natália A. Borges
openaire +4 more sources
Osteoarthritis and gut microbiome
The role of the gutl microbiome within a "gut-joint" axis is increasingly studied in osteoarthritis. The gut microbiome, particularly via its role in low-grade systemic inflammation, could be involved in joint destruction and osteoarthritic pain.
Binvignat, Marie+4 more
openaire +2 more sources
Diabetes and the Gut Microbiome
Gut dysbiosis in diabetes mellitus is associated with decreased short-chain fatty acids and epithelial barrier disruption. Microbial-derived toxins move across the "leaky gut" and incur systemic inflammation and insulin resistance. In children, gut dysbiosis has been associated with risk of developing type 1 diabetes mellitus.
Lau, Wei Ling+4 more
openaire +5 more sources
The gut microbiome and epilepsy [PDF]
Recently, evidence from both animal studies and human cases has emerged that a dysbiosis in the gut may be associated with certain forms of epilepsy. The ketogenic diet is an alternative treatment of drug-resistant epilepsy, although its precise mechanism of action has been unclear.
Maria Dahlin, Stefanie Prast-Nielsen
openaire +3 more sources
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease
Alzheimer’s disease (AD) pathology is thought to progress from normal cognition through preclinical disease and ultimately to symptomatic AD with cognitive impairment.
A. Ferreiro+19 more
semanticscholar +1 more source