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The gut microbiome as a modulator of healthy ageing
The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct.
T. Ghosh, F. Shanahan, P. O’Toole
semanticscholar +1 more source
Material Engineering in Gut Microbiome and Human Health
Tremendous progress has been made in the past decade regarding our understanding of the gut microbiome’s role in human health. Currently, however, a comprehensive and focused review marrying the two distinct fields of gut microbiome and material research
Letao Yang+5 more
doaj +1 more source
Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V+3 more
core +1 more source
The gut microbiome and frailty [PDF]
The human microbiome is constituted by an extensive network of organisms that lie at the host/environment interface and transduce signals that play vital roles in human health and disease across the lifespan. Frailty is a critical aging-related syndrome marked by diminished physiological reserve and heightened vulnerability to stress, predictive of ...
Susan Tuddenham+2 more
openaire +3 more sources
The role of the sex hormone-gut microbiome axis in tumor immunotherapy
Accumulating evidence suggested that both gut microbiome and sex play a critical role in the efficacy of immune checkpoint blockade therapy. Considering the reciprocal relationship between sex hormones and gut microbiome, the sex hormone-gut microbiome ...
Luoyang Wang+10 more
doaj +1 more source
Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]
Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher+8 more
core +1 more source
The composition of the gut microbiome has been associated with clinical responses to immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific microbiome characteristics linked to the clinical benefits of ICIs.
KarlaA Lee+39 more
semanticscholar +1 more source
Prebiotics, faecal transplants and microbial network units to stimulate biodiversity of the human gut microbiome [PDF]
Accumulating evidence demonstrates the intimate association between human hosts and the gut microbiome. Starting at birth, the sterile gut of the newborn acquires a diverse spectrum of microbes, needed for immunological priming.
Biasucci G.+7 more
core +1 more source
Human Skin, Oral, and Gut Microbiomes Predict Chronological Age. [PDF]
Human gut microbiomes are known to change with age, yet the relative value of human microbiomes across the body as predictors of age, and prediction robustness across populations is unknown. In this study, we tested the ability of the oral, gut, and skin
Allaband, Celeste+15 more
core +1 more source
A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders
The human body is full of an extensive number of commensal microbes, consisting of bacteria, viruses, and fungi, collectively termed the human microbiome.
Shokufeh Ghasemian Sorboni+3 more
semanticscholar +1 more source