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Science, 2015
The potential for the gut microbiota to affect health has a particular relevance for older individuals. This is because the microbiota may modulate aging-related changes in innate immunity, sarcopaenia, and cognitive function, all of which are elements of frailty.
Paul W, O'Toole, Ian B, Jeffery
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The potential for the gut microbiota to affect health has a particular relevance for older individuals. This is because the microbiota may modulate aging-related changes in innate immunity, sarcopaenia, and cognitive function, all of which are elements of frailty.
Paul W, O'Toole, Ian B, Jeffery
openaire +2 more sources
Gut Microbiota and the Microvasculature
Cold Spring Harbor Perspectives in Medicine, 2023The gut microbiota is increasingly recognized as an actuating variable shaping vascular development and endothelial cell function in the intestinal mucosa but also affecting the microvasculature of remote organs. In the small intestine, colonization with gut microbiota and subsequent activation of innate immune pathways promotes the development of ...
Klytaimnistra, Kiouptsi +2 more
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Immunoregulation by the gut microbiota
Cellular and Molecular Life Sciences, 2012The human intestinal mucosa is constantly exposed to commensal microbiota. Since the gut microbiota is beneficial to the host, hosts have evolved intestine-specific immune systems to co-exist with the microbiota. On the other hand, the intestinal microbiota actively regulates the host's immune system, and recent studies have revealed that specific ...
Junko, Nishio, Kenya, Honda
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Obesity and the Gut Microbiota
Journal of Clinical Gastroenterology, 2011Gut microorganisms have the potential to influence weight gain and fat deposition through a variety of mechanisms. One factor is the ability of microorganisms in the large intestine to release energy by fermenting otherwise indigestible components of the diet ("energy harvest").
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Nature Immunology, 2020
Paola Ricciardi-Castagnoli describes how her groups’ focus on mucosal immunity led to the discovery of how dendritic cells sense the gut microbiota to maintain homeostasis.
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Paola Ricciardi-Castagnoli describes how her groups’ focus on mucosal immunity led to the discovery of how dendritic cells sense the gut microbiota to maintain homeostasis.
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2018
Understanding how the human gut microbiota might influence ageing is challenging. The gut microbiota is a hugely complex ecology of organisms that varies greatly with individuals and time, making age-related changes difficult to measure. However, elderly and younger populations do show differences in gut microbe composition. The key question is whether
Claire, Maynard, David, Weinkove
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Understanding how the human gut microbiota might influence ageing is challenging. The gut microbiota is a hugely complex ecology of organisms that varies greatly with individuals and time, making age-related changes difficult to measure. However, elderly and younger populations do show differences in gut microbe composition. The key question is whether
Claire, Maynard, David, Weinkove
openaire +2 more sources
Gut microbiota and Hashimoto’s thyroiditis
Reviews in Endocrine and Metabolic Disorders, 2018About two third of the human microbial commensal community, namely the gut microbiota, is hosted by the gastrointestinal tract which represents the largest interface of the organism to the external environment. This microbial community co-evolved in a symbiotic relationship with the human beings.
Virili, Camilla +4 more
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Kwashiorkor and the Gut Microbiota
New England Journal of Medicine, 2013A recent study involving twins from Malawi and mouse models suggests that gut microbiota cause susceptibility to kwashiorkor, a severe form of undernutrition.
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Gut microbiota and atherosclerosis
GutAtherosclerosis reflects a chronic inflammatory process of arteries. The origin of chronic vascular inflammation has been associated over a long time primarily with lipid disorders, but evidence from the past years has suggested that lipid-independent pathways are also involved.
William Fusco +5 more
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2016
The microbiota in our gut performs many different essential functions that help us to stay healthy. These functions include vitamin production, regulation of lipid metabolism and short chain fatty acid production as fuel for epithelial cells and regulation of gene expression.
Harmsen, Hermie J. M. +1 more
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The microbiota in our gut performs many different essential functions that help us to stay healthy. These functions include vitamin production, regulation of lipid metabolism and short chain fatty acid production as fuel for epithelial cells and regulation of gene expression.
Harmsen, Hermie J. M. +1 more
openaire +2 more sources