Potential influence of antimicrobial resistance gene content in probiotic bacteria on the gut resistome ecosystems [PDF]
Frontiers in Nutrition, 2023 Antimicrobial resistance (AMR) poses a substantial threat to human health. The commensal bacteria of the gut microbiome were shown to serve as a reservoir of antibiotic resistance genes (ARGs), termed the gut resistome, which has the potential to ...
Marina Radovanovic +7 more
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Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance [PDF]
Microbiome, 2020 Background The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Kihyun Lee +12 more
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The association between early life antibiotic exposure and the gut resistome of young children: a systematic review [PDF]
Gut Microbes, 2022 Antimicrobial resistance is a growing public health burden, but little is known about the effects of antibiotic exposure on the gut resistome. As childhood (0–5 years) represents a sensitive window of microbiome development and a time of relatively high ...
Rebecca M. Lebeaux +6 more
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Impact of long-term dietary habits on the human gut resistome in the Dutch population [PDF]
Scientific Reports, 2022 The human gut microbiome plays a central role in health and disease. Environmental factors, such as lifestyle and diet, are known to shape the gut microbiome as well as the reservoir of resistance genes that these microbes harbour; the resistome. In this
Paul B. Stege +13 more
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Potential Elimination of Human Gut Resistome by Exploiting the Benefits of Functional Foods [PDF]
Frontiers in Microbiology, 2020 Recent advances in technology over the last decades have strived to elucidate the diverse and abundant ecosystem of the human microbiome. The intestinal microbiota represents a densely inhabited environment that offers a plethora of beneficial effects to
Christina Tsigalou +4 more
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Dose-dependent impact of enrofloxacin on broiler chicken gut resistome is mitigated by synbiotic application [PDF]
Frontiers in Microbiology, 2022 Fluoroquinolone agents are considered critical for human medicine by the World Health Organization (WHO). However, they are often used for the treatment of avian colibacillosis in poultry production, creating considerable concern regarding the potential ...
Robin Temmerman +7 more
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Human gut resistome can be country-specific [PDF]
PeerJ, 2019 The emergence and spread of antibiotic resistance have become emerging threats to human health. The human gut is a large reservoir for antibiotic resistance genes. The gut resistome may be influenced by many factors, but the consumption of antibiotics at
Yao Xia, Yanshan Zhu, Qier Li, Jiahai Lu
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Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome [PDF]
Nature CommunicationsThe assembly of the gut resistome in early life is key to infant health. Specific perinatal factors such as cesarean section (C-section), antibiotic exposure and lack of breastfeeding practices are detrimental to proper microbial development and increase
Anna Samarra +7 more
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The infant gut resistome is associated with E. coli and early-life exposures [PDF]
BMC Microbiology, 2021 Background The human gut microbiome harbors a collection of bacterial antimicrobial resistance genes (ARGs) known as the resistome. The factors associated with establishment of the resistome in early life are not well understood.
Rebecca M. Lebeaux +9 more
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High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic study [PDF]
npj Biofilms and MicrobiomesAntimicrobial resistance (AMR) is a global health challenge. The gut microbiome, a major reservoir for AMR, is influenced by dietary habits. However, the specific impact of dietary patterns on gut resistome remains poorly understood.
Yingbo Shen +13 more
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