Results 41 to 50 of about 3,179 (151)

Differential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults

open access: yesNature Communications, 2023
Despite their crucial importance for human health, there is still relatively limited knowledge on how the gut resistome changes or responds to antibiotic treatment across ages, especially in the latter case.
Xuanji Li   +9 more
doaj   +1 more source

The human gut resistome [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain.
openaire   +2 more sources

Abundance and diversity of resistomes differ between healthy human oral cavities and gut

open access: yesNature Communications, 2020
Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of ...
Victoria R. Carr   +7 more
doaj   +1 more source

Identification of aminoglycoside and β-lactam resistance genes from within an infant gut functional metagenomic library. [PDF]

open access: yesPLoS ONE, 2014
The infant gut microbiota develops rapidly during the first 2 years of life, acquiring microorganisms from diverse sources. During this time, significant opportunities exist for the infant to acquire antibiotic resistant bacteria, which can become ...
Fiona Fouhy   +8 more
doaj   +1 more source

Characterization of Resistome in Lactobacillus Genomic Sequences From the Human Gut

open access: yesJournal of Global Antimicrobial Resistance, 2022
Abstract The gut is a complex environment inhabited by a wide range of bacterial species. Lactobacillus species constitute a significant proportion of this environment, and, due to their mobile genetic elements such as plasmids and transposons, are more likely to acquire and transfer antibiotic resistance genes through horizontal gene transfer (
Jale Moradi   +6 more
openaire   +3 more sources

Antibiotic perturbation of the preterm infant gut microbiome and resistome [PDF]

open access: yesGut Microbes, 2016
The gut microbiota plays important roles in nutrient absorption, immune system development, and pathogen colonization resistance. Perturbations early in life may be detrimental to host health in the short and the long-term. Antibiotics are among the many factors that influence the development of the microbiota.
Andrew J, Gasparrini   +5 more
openaire   +2 more sources

The gut microbiome and resistome of conventionally vs. pasture-raised pigs

open access: yesMicrobial Genomics, 2023
Conventional swine production typically houses pigs indoors and in large groups, whereas pasture-raised pigs are reared outdoors at lower stocking densities. Antimicrobial use also differs, with conventionally raised pigs often being exposed to antimicrobials directly or indirectly to control and prevent infectious disease. However,
Devin B. Holman   +2 more
openaire   +2 more sources

Impacts of dietary copper on the swine gut microbiome and antibiotic resistome [PDF]

open access: yesScience of The Total Environment, 2023
Restrictions on antibiotic growth promoters have prompted livestock producers to use alternative growth promoters, and dietary copper (Cu) supplementation is currently being widely used in pig production. However, elevated doses of dietary Cu constitute a risk for co-selection of antibiotic resistance and the risk may depend on the type of Cu-based ...
Brinck, Julius Emil   +10 more
openaire   +6 more sources

Characterization of the Gut Microbiome and Resistomes of Wild and Zoo-Captive Macaques [PDF]

open access: yesFrontiers in Veterinary Science, 2022
Rhesus macaques (Macaca mulatta) are the most widely distributed species of Old World monkey and are frequently used as animal models to study human health and disease. Their gastrointestinal microbial community likely plays a major role in their physiology, ecology and evolution. Herein, we compared the fecal microbiome and antibiotic resistance genes
Ting Jia   +10 more
openaire   +4 more sources

Social demographics determinants for resistome and microbiome variation of a multiethnic community in Southern Malaysia

open access: yesnpj Biofilms and Microbiomes, 2023
The prevalence of antibiotic-resistant bacteria in Southeast Asia is a significant concern, yet there is limited research on the gut resistome and its correlation with lifestyle and environmental factors in the region. This study aimed to profile the gut
J. Dwiyanto   +8 more
doaj   +1 more source

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