Results 41 to 50 of about 7,589 (207)

Analysis of 1135 gut metagenomes identifies sex-specific resistome profiles [PDF]

Gut Microbes, 2018
Several gastrointestinal diseases show a sex imbalance, although the underlying (patho)physiological mechanisms behind this are not well understood. The gut microbiome may be involved in this process, forming a complex interaction with host immune system, sex hormones, medication and other environmental factors.
Sinha, Trishla, Vich Vila, Arnau, Garmaeva, Sanzhima, Jankipersadsing, Soesma A., Imhann, Floris, Collij, Valerie, Bonder, Marc Jan, Jiang, Xiaofang, Gurry, Thomas, Alm, Eric J., D’Amato, Mauro, Weersma, Rinse K., Scherjon, Sicco, Wijmenga, Cisca, Fu, Jingyuan, Kurilshikov, Alexander, Zhernakova, Alexandra   +16 more
openaire   +5 more sources

A reference gene catalogue of chicken gut antibiotic resistomes [PDF]

, 2021
Abstract Background: The chicken gut microbiota, as a reservoir of antibiotic resistance genes (ARGs), poses a high risk to humans and animals worldwide. Yet a comprehensive exploration of the chicken gut antibiotic resistomes remains incomplete.
Jintao Yang, Cuihong Tong, Danyu Xiao, Longfei Xie, Ruonan Zhao, Zhipeng Huo, Ziyun Tang, Jie Hao, Zhenling Zeng, Wenguang Xiong   +9 more
openaire   +1 more source

Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]

, 2018
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher, Burnham, Carey-Ann D, CDC Prevention Epicenter Program,, Dantas, Gautam, Dubberke, Erik R, Hink, Tiffany, Jones, Susan, Kwon, Jennie H, Langdon, Amy, Patel, Sanket, Reske, Kimberly A, Seiler, Sondra, Sun, Xiaoqing, Wallace, Meghan   +13 more
core   +2 more sources

Country-specific antibiotic use practices impact the human gut resistome [PDF]

Genome Research, 2013
Despite increasing concerns over inappropriate use of antibiotics in medicine and food production, population-level resistance transfer into the human gut microbiota has not been demonstrated beyond individual case studies. To determine the “antibiotic resistance potential” for entire microbial communities, we employ metagenomic data and quantify the ...
Forslund, Kristoffer, Sunagawa, Shinichi, Kultima, Jens Roat, Mende, Daniel R, Arumugam, Manimozhiyan, Typas, Athanasios, Bork, Peer   +6 more
openaire   +4 more sources

The gut microbiome and resistome of conventionally vs. pasture-raised pigs

Microbial Genomics, 2023
Conventional swine production typically houses pigs indoors and in large groups, whereas pasture-raised pigs are reared outdoors at lower stocking densities. Antimicrobial use also differs, with conventionally raised pigs often being exposed to antimicrobials directly or indirectly to control and prevent infectious disease. However,
Devin B. Holman, Katherine E. Gzyl, Arun Kommadath   +2 more
openaire   +2 more sources

Social demographics determinants for resistome and microbiome variation of a multiethnic community in Southern Malaysia

npj Biofilms and Microbiomes, 2023
The prevalence of antibiotic-resistant bacteria in Southeast Asia is a significant concern, yet there is limited research on the gut resistome and its correlation with lifestyle and environmental factors in the region. This study aimed to profile the gut
J. Dwiyanto, M. A. L. Huët, M. H. Hussain, T. T. Su, J. B. L. Tan, K. Y. Toh, J. W. J. Lee, S. Rahman, C. W. Chong   +8 more
doaj   +1 more source

Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]

, 2015
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D., Fouhy, Fiona, Hill, Colin, STANTON, CATHERINE, Walsh, Fiona   +4 more
core   +1 more source

Phylogeny, Resistome, and Virulome of Escherichia coli Causing Biliary Tract Infections [PDF]

, 2019
Escherichia coli is the most frequent Gram-negative bacilli involved in intra-abdominal infections. However, despite high mortality rates associated with biliary tract infections due to E. coli, there is no study focusing on this pathogen. In this study,
Aznar Martín, Javier, Bonnin, Rémy A., Lepe, José A., Naas, Thierry, Ortiz de la Rosa, José Manuel, Pachón, Jerónimo, Rodríguez-Villodres, Ángel, Smani, Younes, Álvarez-Marín, Rocío   +8 more
core   +2 more sources

Antibiotic perturbation of the preterm infant gut microbiome and resistome [PDF]

Gut Microbes, 2016
The gut microbiota plays important roles in nutrient absorption, immune system development, and pathogen colonization resistance. Perturbations early in life may be detrimental to host health in the short and the long-term. Antibiotics are among the many factors that influence the development of the microbiota.
Andrew J, Gasparrini, Terence S, Crofts, Molly K, Gibson, Phillip I, Tarr, Barbara B, Warner, Gautam, Dantas   +5 more
openaire   +2 more sources

Gut microbiota research nexus: One Health relationship between human, animal, and environmental resistomes [PDF]

mLife, 2023
AbstractThe emergence and rapid spread of antimicrobial resistance is of global public health concern. The gut microbiota harboring diverse commensal and opportunistic bacteria that can acquire resistance via horizontal and vertical gene transfers is considered an important reservoir and sink of antibiotic resistance genes (ARGs).
Yuhao Fu, Qingyuan Dou, Kornelia Smalla, Yu Wang, Timothy A. Johnson, Kristian K. Brandt, Zhi Mei, Maoyuan Liao, Syed A. Hashsham, Andreas Schäffer, Hauke Smidt, Tong Zhang, Hui Li, Robert Stedtfeld, Hongjie Sheng, Benli Chai, Marko Virta, Xin Jiang, Fang Wang, Yong‐Guan Zhu, James M. Tiedje   +20 more
openaire   +7 more sources