Results 51 to 60 of about 3,179 (151)

ResistoMap—online visualization of human gut microbiota antibiotic resistome [PDF]

Bioinformatics, 2016
Abstract We created ResistoMap—a Web-based interactive visualization of the presence of genetic determinants conferring resistance to antibiotics, biocides and heavy metals in human gut microbiota. ResistoMap displays the data on more than 1500 published gut metagenomes of world populations including both healthy subjects and patients.
Konstantin S. Yarygin, Boris Kovarsky, Tanya Bibikova, Damir Melnikov, Alexander V. Tyakht, Dmitry G. Alexeev   +5 more
openaire   +2 more sources

Antibiotic resistomes discovered in the gut microbiomes of Korean swine and cattle [PDF]

GigaScience, 2020
Abstract Background Antibiotics administered to farm animals have led to increasing prevalence of resistance genes in different microbiomes and environments. While antibiotic treatments help cure infectious diseases in farm animals, the possibility of spreading antibiotic resistance genes into the ...
Suk-Kyung Lim, Dongjun Kim, Dong-Chan Moon, Youna Cho, Mina Rho   +4 more
openaire   +2 more sources

Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome

Gut Microbes, 2022
A global rise in antimicrobial resistance among pathogenic bacteria has proved to be a major public health threat, with the rate of multidrug-resistant bacterial infections increasing over time.
Alexander Crits-Christoph, Haley Anne Hallowell, Kalia Koutouvalis, Jotham Suez   +3 more
doaj   +1 more source

Effects of selective digestive decontamination (SDD) on the gut resistome

Journal of Antimicrobial Chemotherapy, 2014
Selective digestive decontamination (SDD) is an infection prevention measure for critically ill patients in intensive care units (ICUs) that aims to eradicate opportunistic pathogens from the oropharynx and intestines, while sparing the anaerobic flora, by the application of non-absorbable antibiotics.
Buelow, E., Bello Gonzalez, T.D.G., Versluis, D., Oostdijk, E.A.N., Ogilvie, L.A., van Mourik, M.S.M., Oosterink, L., van Passel, M.W.J., Smidt, H., D’Andrea, M.M., de Been, M., Jones, B.V., Willems, R.J.L., Bonten, M.J.M., Schaik, W.   +14 more
openaire   +6 more sources

Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients

Gut Microbes, 2022
Dysbiosis of gut microbiota is well-described in patients with coronavirus 2019 (COVID-19), but the dynamics of antimicrobial resistance genes (ARGs) reservoir, known as resistome, is less known.
Qi Su, Qin Liu, Lin Zhang, Zhilu Xu, Chenyu Liu, Wenqi Lu, Jessica YL Ching, Amy Li, Joyce Wing Yan Mak, Grace Chung Yan Lui, Susanna So Shan Ng, Kai Ming Chow, David SC Hui, Paul KS Chan, Francis Ka Leung Chan, Siew C Ng   +15 more
doaj   +1 more source

Temporal development and potential interactions between the gut microbiome and resistome in early childhood

Microbiology Spectrum
Antimicrobial resistance-associated infections have become a major threat to global health. The gut microbiome serves as a major reservoir of bacteria with antibiotic resistance genes; whereas, the temporal development of gut resistome during early ...
Lanlan Zhao, Xiao Yang, Yijia Liang, Ziyi Zhang, Yanwen Ding, Yihui Wang, Bin Chen, Jiacheng Wu, Chuandi Jin, Guoping Zhao, Ziyun Li, Lei Zhang   +11 more
doaj   +1 more source

Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome [PDF]

Nature Microbiology, 2016
Development of the preterm infant gut microbiota is emerging as a critical research priority(1). Since preterm infants almost universally receive early and often extended antibiotic therapy(2), it is important to understand how these interventions alter gut microbiota development(3-6).
Molly K, Gibson, Bin, Wang, Sara, Ahmadi, Carey-Ann D, Burnham, Phillip I, Tarr, Barbara B, Warner, Gautam, Dantas   +6 more
openaire   +2 more sources

Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance

Microbiome, 2020
Background The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Kihyun Lee, Dae-Wi Kim, Do-Hoon Lee, Yong-Seok Kim, Ji-Hye Bu, Ju-Hee Cha, Cung Nawl Thawng, Eun-Mi Hwang, Hoon Je Seong, Woo Jun Sul, Elizabeth M. H. Wellington, Christopher Quince, Chang-Jun Cha   +12 more
doaj   +1 more source

Characterization of Wild and Captive Baboon Gut Microbiota and Their Antibiotic Resistomes [PDF]

mSystems, 2018
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts. However, little is known about the state of these communities in the era before the widespread introduction of antibiotics into clinical and agricultural practice.
Pablo Tsukayama, Manish Boolchandani, Sanket Patel, Erica C. Pehrsson, Molly K. Gibson, Kenneth L. Chiou, Clifford J. Jolly, Jeffrey Rogers, Jane E. Phillips‐Conroy, Gautam Dantas   +9 more
openaire   +5 more sources

Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children [PDF]

Scientific Reports, 2016
AbstractThe gut microbiome represents an important reservoir of antibiotic resistance genes (ARGs). Effective methods are urgently needed for managing the gut resistome to fight against the antibiotic resistance threat. In this study, we show that a gut microbiota-targeted dietary intervention, which shifts the dominant fermentation of gut bacteria ...
Guojun Wu, Chenhong Zhang, Jing Wang, Feng Zhang, Ruirui Wang, Jian Shen, Linghua Wang, Xiaoyan Pang, Xiaojun Zhang, Liping Zhao, Menghui Zhang   +10 more
openaire   +2 more sources