Results 71 to 80 of about 7,589 (207)

Dynamic associations between the respiratory tract and gut antibiotic resistome of patients with COVID-19 and its prediction power for disease severity

Gut Microbes, 2023
The antibiotic resistome is the collection of all antibiotic resistance genes (ARGs) present in an individual. Whether an individual’s susceptibility to infection and the eventual severity of coronavirus disease 2019 (COVID-19) is influenced by their ...
Yifei Shen, Wenxin Qu, Fei Yu, Dan Zhang, Qianda Zou, Dongsheng Han, Mengxiao Xie, Xiao Chen, Lingjun Yuan, Bin Lou, Guoliang Xie, Ruonan Wang, Xianzhi Yang, Weizhen Chen, Qi Wang, Yun Teng, Yuejiao Dong, Li Huang, Jiaqi Bao, Chang Liu, Wei Wu, Enhui Shen, Longjiang Fan, Michael P. Timko, Shufa Zheng, Yu Chen   +25 more
doaj   +1 more source

Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs [PDF]

, 2013
Rates of infection with antibiotic-resistant bacteria have increased precipitously over the past several decades, with far-reaching healthcare and societal costs.
Ahmadi, Sara, Dantas, Gautam, Forsberg, Kevin J, Gibson, Molly K, Pehrsson, Erica C   +4 more
core   +2 more sources

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant, Ingeborg M. van Geijlswijk, Mathias Devreese, Marc Cherlet, Leo F. van Geest, Jaap A. Wagenaar, Jan A. M. Langermans, Aldert L. Zomer, Jaco Bakker, Ronette Gehring   +9 more
wiley   +1 more source

Landscape of human gut antibiotic resistome and progression of diabetes [PDF]

, 2021
Objective: To investigate the association between human gut antibiotic resistome and the progression of type 2 diabetes (T2D) in a large cohort study. Design: The present study included 1210 participants from the Guangzhou Nutrition and Health Study. We depicted the landscape of human gut antibiotic resistome with shotgun metagenomic data and examined ...
Menglei Shuai, Guoqing Zhang, Fang-fang Zeng, Yuanqing Fu, Xinxiu Liang, Ling Yuan, Fengzhe Xu, Wanglong Gou, Zelei Miao, Zengliang Jiang, Jia-ting Wang, Lai-bao Zhuo, Yu-ming Chen, Feng Ju, Ju-Sheng Zheng   +14 more
openaire   +1 more source

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

Advanced Science, Volume 13, Issue 20, 9 April 2026.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding, Mengying Wang, Xiaoqing Xu, Dou Wang, Xi Chen, Shuxian Li, Xiawan Zheng, You Che, Yu Deng, Tommy T. Y. Lam, Liguan Li, Tong Zhang   +11 more
wiley   +1 more source

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Gut Microbiome and Putative Resistome of Inca and Italian Nobility Mummies [PDF]

Genes, 2017
Little is still known about the microbiome resulting from the process of mummification of the human gut. In the present study, the gut microbiota, genes associated with metabolism, and putative resistome of Inca and Italian nobility mummies were characterized by using high-throughput sequencing. The Italian nobility mummies exhibited a higher bacterial
Santiago-Rodriguez, Tasha M, Fornaciari, Gino, Luciani, Stefania, Toranzos, Gary A, Marota, Isolina, Giuffra, Valentina, Cano, Raul J.   +6 more
openaire   +2 more sources

Infant age inversely correlates with gut carriage of resistance genes, reflecting modifications in microbial carbohydrate metabolism during early life

iMeta
The infant gut microbiome is increasingly recognized as a reservoir of antibiotic resistance genes, yet the assembly of gut resistome in infants and its influencing factors remain largely unknown.
Xinming Xu, Qingying Feng, Tao Zhang, Yunlong Gao, Qu Cheng, Wanqiu Zhang, Qinglong Wu, Ke Xu, Yucan Li, Nhu Nguyen, Diana H. Taft, David A. Mills, Danielle G. Lemay, Weiyun Zhu, Shengyong Mao, Anyun Zhang, Kelin Xu, Jinxin Liu   +17 more
doaj   +1 more source

The gut microbiome and resistome of yellow perch (Perca flavescens) living in Minnesota lakes under varying anthropogenic pressure

One Health
Anthropogenic activities can significantly impact wildlife in natural water bodies, affecting not only the host's physiology but also its microbiome.
Omar Jimenez-Lopez, Tui Ray, Christopher Dean, Ilya Slizovskiy, Jessica Deere, Tiffany Wolf, Seth Moore, Alexander Primus, Jennifer Høy-Petersen, Silje Finstad, Jakob Mo, Henning Sørum, Noelle Noyes   +12 more
doaj   +1 more source

Gut resistome plasticity in pediatric patients undergoing hematopoietic stem cell transplantation. [PDF]

Sci Rep, 2019
AbstractThe gut microbiome of pediatric patients undergoing allo-hematopoietic stem cell transplantation (HSCT) has recently been considered as a potential reservoir of antimicrobial resistance, with important implications in terms of patient mortality rate. By means of shotgun metagenomics, here we explored the dynamics of the gut resistome – i.e. the
D'Amico F, Soverini M, Zama D, Consolandi C, Severgnini M, Prete A, Pession A, Barone M, Turroni S, Biagi E, Brigidi P, Masetti R, Rampelli S, Candela M.   +13 more
europepmc   +4 more sources