Results 71 to 80 of about 7,489 (208)

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs [PDF]

, 2013
Rates of infection with antibiotic-resistant bacteria have increased precipitously over the past several decades, with far-reaching healthcare and societal costs.
Ahmadi, Sara, Dantas, Gautam, Forsberg, Kevin J, Gibson, Molly K, Pehrsson, Erica C   +4 more
core   +2 more sources

Effects of selective digestive decontamination (SDD) on the gut resistome

Journal of Antimicrobial Chemotherapy, 2014
Selective digestive decontamination (SDD) is an infection prevention measure for critically ill patients in intensive care units (ICUs) that aims to eradicate opportunistic pathogens from the oropharynx and intestines, while sparing the anaerobic flora, by the application of non-absorbable antibiotics.
Buelow, E., Bello Gonzalez, T.D.G., Versluis, D., Oostdijk, E.A.N., Ogilvie, L.A., van Mourik, M.S.M., Oosterink, L., van Passel, M.W.J., Smidt, H., D’Andrea, M.M., de Been, M., Jones, B.V., Willems, R.J.L., Bonten, M.J.M., Schaik, W.   +14 more
openaire   +6 more sources

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant, Ingeborg M. van Geijlswijk, Mathias Devreese, Marc Cherlet, Leo F. van Geest, Jaap A. Wagenaar, Jan A. M. Langermans, Aldert L. Zomer, Jaco Bakker, Ronette Gehring   +9 more
wiley   +1 more source

Landscape of human gut antibiotic resistome and progression of diabetes [PDF]

, 2021
Objective: To investigate the association between human gut antibiotic resistome and the progression of type 2 diabetes (T2D) in a large cohort study. Design: The present study included 1210 participants from the Guangzhou Nutrition and Health Study. We depicted the landscape of human gut antibiotic resistome with shotgun metagenomic data and examined ...
Menglei Shuai, Guoqing Zhang, Fang-fang Zeng, Yuanqing Fu, Xinxiu Liang, Ling Yuan, Fengzhe Xu, Wanglong Gou, Zelei Miao, Zengliang Jiang, Jia-ting Wang, Lai-bao Zhuo, Yu-ming Chen, Feng Ju, Ju-Sheng Zheng   +14 more
openaire   +1 more source

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, EarlyView.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source

Gut resistome plasticity in pediatric patients undergoing hematopoietic stem cell transplantation. [PDF]

Sci Rep, 2019
AbstractThe gut microbiome of pediatric patients undergoing allo-hematopoietic stem cell transplantation (HSCT) has recently been considered as a potential reservoir of antimicrobial resistance, with important implications in terms of patient mortality rate. By means of shotgun metagenomics, here we explored the dynamics of the gut resistome – i.e. the
D'Amico F, Soverini M, Zama D, Consolandi C, Severgnini M, Prete A, Pession A, Barone M, Turroni S, Biagi E, Brigidi P, Masetti R, Rampelli S, Candela M.   +13 more
europepmc   +4 more sources

Dichotomous development of the gut microbiome in preterm infants. [PDF]

, 2018
BackgroundPreterm infants are at risk of developing intestinal dysbiosis with an increased proportion of Gammaproteobacteria. In this study, we sought the clinical determinants of the relative abundance of feces-associated Gammaproteobacteria in very low
Gilbert, Jack A, Groer, Maureen W, Ho, Thao TB, Kane, Bradley, Maheshwari, Akhil, Torres, Benjamin A, Yee, Alyson L   +6 more
core   +1 more source

Whole‐Genome Sequence Profiling of Listeria innocua From Different Sources: Implications for Public Health

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The studied strains, LIN_NWU_CNKT and LIN5_NWU_CNKT, exhibit invasiveness, pathogenicity, and MDR profiles. The isolation of these strains from food products and water underscores their significant public health implications, particularly in the context of the “One Health” concept.
Christ‐Donald Kaptchouang Tchatchouang, Daniel Jesuwenu Ajose, Giulia Amagliani, Collins Njie Ateba   +3 more
wiley   +1 more source

Gut Microbiome and Putative Resistome of Inca and Italian Nobility Mummies [PDF]

Genes, 2017
Little is still known about the microbiome resulting from the process of mummification of the human gut. In the present study, the gut microbiota, genes associated with metabolism, and putative resistome of Inca and Italian nobility mummies were characterized by using high-throughput sequencing. The Italian nobility mummies exhibited a higher bacterial
Santiago-Rodriguez, Tasha M, Fornaciari, Gino, Luciani, Stefania, Toranzos, Gary A, Marota, Isolina, Giuffra, Valentina, Cano, Raul J.   +6 more
openaire   +2 more sources