Results 51 to 60 of about 748 (103)

The challenge of prioritising across phenotypically complex traits in breeding for highly variable environments

, 2016
Genome-wide association studies (GWASs) have been successful in discovering SNP trait associations for many quantitative traits and common diseases. Typically, the effect sizes of SNP alleles are very small and this requires large genome-wide association
Cocks, N., Rebetzke, G., Cullis, B., Smith, A., Chenu, K.   +4 more
core  

Genetic dissection of serum pro-neurotensin suggests potential causal impact on brain structure. [PDF]

EBioMedicine
Breitfeld J, Horn K, Velluva A, Beyer F, Pott J, Baber R, Stumvoll M, Le Duc D, Witte V, Giontella A, Melander O, Kovacs P, Scholz M, Tönjes A.   +13 more
europepmc   +1 more source

Replication of 10 novel loci involved in human plasma protein N-glycosylation using MALDI-MS and UHPLC-FD data. [PDF]

Glycobiology
Timoshchuk A, Naber A, Slieker R, Soplenkova A, Maslov DE, Potapova NA, Nicolardi S, Elders PJM, Sijbrands EJG, Sharapov S, 't Hart LM, van Hoek M, Wuhrer M, Aulchenko YS.   +13 more
europepmc   +1 more source

Integrative multivariate genomic analysis reveals shared genetic determinants and druggable targets for vascular calcification. [PDF]

Front Med (Lausanne)
Li H, Li G.
europepmc   +1 more source

Multi-ancestry genetic architecture of heart failure subtypes. [PDF]

Nat Commun
Liu C, Hui Q, Linchangco GV, Wells QS, Farber-Eger E, Rasooly D, Michael Gaziano J, Wilson PWF, Quyyumi AA, Vaccarino V, Hu YJ, Benkeser D, Ito K, Enzan N, VA Million Veteran Program, Phillips LS, Joseph J, Sun YV.   +17 more
europepmc   +1 more source

Health Care Service Readiness and Quality of Care for Sexual Violence in Garissa, Kwale, Narok, and West Pokot Counties, Kenya: A Mixed-Methods Study. [PDF]

Glob Health Sci Pract
Njogu J, Ndung'u L, Momanyi H, Nthumbi M, Wambua A, Zaid H, Pahe C, Gwama F, Malmqvist A, Rothschild CW.   +9 more
europepmc   +1 more source

Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci. [PDF]

Front Genet, 2021
Bellomo TR, Bone WP, Chen BY, Gawronski KAB, Zhang D, Park J, Levin M, Tsao N, Klarin D, Lynch J, Assimes TL, Gaziano JM, Wilson PW, Cho K, Vujkovic M, O'Donnell CJ, Chang KM, Tsao PS, Rader DJ, Ritchie MD, Damrauer SM, Voight BF.   +21 more
europepmc   +1 more source

KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans. [PDF]

Nat Commun
Kamiza AB, Chikowore T, Chen G, Ojewunmi O, Machipisa T, Zhou F, Mayanja R, Toure S, Soremekun O, Kintu C, Nakabuye M, Koprulu M, Kalungi A, Kalyesubula R, Salako B, Nashiru O, Corpas M, Robinson-Cohen C, Franceschini N, Pattaro C, Köttgen A, Nitsch D, Langenberg C, Tcheandjieu C, Nyirenda M, Morris AP, Asimit J, Zeggini E, Rotimi C, Ramsay M, Adeyemo A, Fabian J, Crampin AC, Brandenburg JT, Fatumo S.   +34 more
europepmc   +1 more source

Dissecting the genetic and proteomic risk factors for delirium. [PDF]

Nat Aging
Raptis V, Bhak Y, Cannings TI, MacLullich AMJ, Tenesa A.   +4 more
europepmc   +1 more source

A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins. [PDF]

Nat Commun
Sharapov S, Timoshchuk A, Zaytseva O, Maslov DE, Soplenkova A, Elgaeva EE, Tiys ES, Mangino M, Wittenbecher C, Karssen L, Timofeeva M, Nostaeva A, Vuckovic F, Trbojević-Akmačić I, Štambuk T, Feoktistova S, Potapova NA, Voroshilova V, Williams F, Primorac D, Van Zundert J, Georges M, Suhre K, Allegri M, Chaturvedi N, Dunlop M, Schulze MB, Spector T, Tsepilov YA, Lauc G, Aulchenko YS.   +30 more
europepmc   +1 more source