Results 111 to 120 of about 247,905 (333)

Oral Microbiota and Pharyngeal-Laryngeal Cancer Risk: Evidence from Mendelian Randomization in East Asian Populations

Polish Journal of Microbiology
Pharyngeal and laryngeal cancer (PLC) encompasses a range of aggressive malignancies associated with substantial clinical impact, underscoring the need for novel preventive and therapeutic measures.
FU JINGFENG
doaj   +1 more source

Single nucleotide variants rs6582147, rs10010305, rs2136810, rs17797829 as new molecular genetic markers of sudden cardiac death

Российский кардиологический журнал, 2018
Aim. To confirm association between sudden cardiac death (SCD) and single nucleotide polymorphisms rs6582147 rs 10010305, rs2136810, rs17797829, identified as the most likely candidate markers.Material and methods. The SCD group (n=360, mean age 53,0±9,2
A. A. Ivanova, V. N. Maksimov, D. I. Moiseeva, S. K. Malyutina, V. P. Novoselov, M. I. Voevoda   +5 more
doaj   +1 more source

High Prevalence of SOD1 Pathogenic Variants in the UK Biobank: Implications for Early Intervention in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective SOD1 is the second most frequently mutated gene in European patients with amyotrophic lateral sclerosis (ALS). Given the recent authorization of SOD1‐targeted antisense oligonucleotides for SOD1‐ALS, prompt screening for SOD1 mutations in patients with ALS patients is highly recommended.
Delia Gagliardi, Chiara Villella, Matteo Zanovello, Virginia Iacobelli, Stefania Corti, Giacomo Pietro Comi, Pietro Fratta, Henry Houlden, Arianna Tucci, Dario Ronchi   +9 more
wiley   +1 more source

Identification of Superior Alleles for Seedling Stage Salt Tolerance in the USDA Rice Mini-Core Collection

Plants, 2019
Salt stress is a major constraint to rice acreage and production worldwide. The purpose of this study was to evaluate the natural genetic variation available in the United States Department of Agriculture (USDA) rice mini-core collection (URMC) for early
Jai S. Rohila, Jeremy D. Edwards, Gioi D. Tran, Aaron K. Jackson, Anna M. McClung   +4 more
doaj   +1 more source

Enabling Privacy-Preserving GWAS in Heterogeneous Human Populations [PDF]

, 2016
Sean Simmons, Cenk Sahinalp, Bonnie Berger   +2 more
openalex   +1 more source

Additional file 1 of Identifying novel proteins underlying schizophrenia via integrating pQTLs of the plasma, CSF, and brain with GWAS summary data

, 2023
Xiaojing Gu, Meng Dou, Wei‐Ming Su, Zheng Jiang, Qing‐Qing Duan, Bei Cao, Yongping Chen   +6 more
openalex   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Life After GWAS [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2012
The genome-wide association studies (GWAS) of recent years have provided the first unbiased views of genes contributing to cardiovascular disorders in European and some Asian and African populations. In addition to extending these studies using techniques such as deep sequencing, the major challenge at present is to understand how the novel genes ...
openaire   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source

Gene Hunting with Knockoffs for Hidden Markov Models

, 2017
Modern scientific studies often require the identification of a subset of relevant explanatory variables, in the attempt to understand an interesting phenomenon. Several statistical methods have been developed to automate this task, but only recently has
Candès, Emmanuel J., Sabatti, Chiara, Sesia, Matteo   +2 more
core   +1 more source