Identification of <i>IL7R</i> as a key genetic risk locus in childhood steroid-sensitive nephrotic syndrome and IgA nephropathy. [PDF]
Wang C +19 more
europepmc +1 more source
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann +30 more
wiley +1 more source
Association-Based Analysis of Verticillium Wilt Resistance in a Bi-Parental Hop (<i>Humulus lupulus</i> L.) Population for Marker Development in Breeding. [PDF]
Luskar L +6 more
europepmc +1 more source
Is quinoa‐farming sustainable in marginal environments? Social, economical and environmental aspects
Abstract Quinoa (Chenopodium quinoa Willd.) is an Andean grain crop introduced as a novel crop to many parts of the world in recent years. Recognized for nutritious seeds and high abiotic stress tolerance, it has been promoted as an element of climate‐resilient agriculture, particularly in marginal environments.
Anna Tabea Mengen +5 more
wiley +1 more source
From QTL mapping to genome editing: advances and integrated strategies for improving aluminum tolerance in crops. [PDF]
Liu Y, Chen C, Zhu H, Yang J.
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong +4 more
wiley +1 more source
ABSTRACT Epigenetic clocks are robust biomarkers of biological aging and have been associated with cancer susceptibility. However, the relationship between genetically predicted epigenetic age acceleration and head and neck cancer risk remains unclear. Using a large case‐control study of 2189 head and neck squamous cell carcinoma (HNSCC) cases and 2189
Jiaqi Wang +9 more
wiley +1 more source
Ultra-fast genetic colocalisation across millions of association signals. [PDF]
Jesse M, Riet AE, Alasoo K.
europepmc +1 more source
Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe +15 more
wiley +1 more source
Identification of Shared Genetic Variants and Haplotypes Associated With Schizophrenia and Depression. [PDF]
Gholami M.
europepmc +1 more source

