Results 151 to 160 of about 198,268 (313)

Digesting GWAS [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2016
openaire   +3 more sources

A Pilot Randomized Study of NAT2 and YEATS4 Pharmacogenetic Return of Results in Adults with Hypertension and African Ancestry: The GUARDD‐US PGx Study

Clinical Pharmacology &Therapeutics, EarlyView.
Almost half of individuals with hypertension fail to achieve recommended blood pressure (BP) goals. Pharmacogenetic gene‐drug interactions may alter the efficacy of antihypertensive agents. We conducted a multicenter randomized controlled sub‐study of participants (N = 1874) with hypertension and self‐reported African ancestry to determine whether ...
Philip E. Empey, Nita A. Limdi, Dinushika Mohottige, Kady‐Ann Steen‐Burrell, Hrishikesh Chakraborty, Khoa A. Nguyen, Alexander S. Parker, Emily J. Cicali, Girish N. Nadkarni, Michelle A. Ramos, Sabrina Clermont, Erica N. Elwood, Mimsie Robinson, Nandini Shroff, Marc B. Rosenman, Ronald Huang, Larisa H. Cavallari, Julie A. Johnson, Paul R. Dexter, Todd C. Skaar, Kerri L. Cavanaugh, Christina M. Wyatt, Carol R. Horowitz, Rhonda M. Cooper‐DeHoff, Michael T. Eadon, on behalf of the IGNITE Pragmatic Trials Network   +25 more
wiley   +1 more source

SNPs detected in GWAS.

, 2019
SNPs detected in GWAS.
Tsuyoshi Tokunaga (6445808), Masaaki Kobayashi (5130710), Kentaro Yano (15286), Toru Kudo (7907777), Hiromi Kajiya-Kanegae (5993417), Hiroyoshi Iwata (487190), Hideki Takanashi (7907774), Nobuhiro Tsutsumi (200410), Lisa Sakamoto (7907771), Koji Noshita (3326502)   +9 more
core   +1 more source

The Language of Greenwashing: SDG Omission and Opportunity‐Oriented Environmental Tone as Alert Metrics in Green Bond Disclosures

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Green bonds play a central role in sustainable finance, yet concerns about greenwashing raise questions about the credibility of issuers' sustainability disclosures. Using dictionary‐based methods and domain‐specific BERT transformer models, this paper proposes two greenwashing alert metrics and investigates their performance by analyzing ...
Andrea Nicolodi, Sandra Paterlini, Monica Gentile, Vincenzo Foglia Manzillo, Gianluca Vittorioso   +4 more
wiley   +1 more source

Integrative Genomic and Functional Investigation of the Multi‐Layered Genetic Architecture Between Anorexia Nervosa and Bone Loss

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Bone loss is a severe and often irreversible complication of anorexia nervosa (AN), yet the genetic mechanisms underlying this comorbidity remain underexplored. This study focuses on constructing a comprehensive genetic architecture between AN and estimated calcaneal bone mineral density (eBMD).
Tao Han, Yuke Wang, Yixiong Dang, Rong Xiang, Yan Zeng, Sheng He, Ye Ju, Zilan Chen, Ting Liu, Zihao Li, Yuqi Pang, Wanyi Tan, Jue Xu, Jingwen Jiang, Xia Jiang   +14 more
wiley   +1 more source

The human genome and the gut microbiome: molecular mechanisms of interaction in the context of the holobiont concept

Patologìâ
Over the last decade, scientific understanding of the human body has shifted from an anthropocentric model to the concept of the holobiont – an integrated ecological unit consisting of the host and its microbiome. The interaction between the human genome
O. O. Kremzer , O. V. Kraidashenko, O. O. Kraidashenko   +2 more
doaj   +1 more source

Quality control and its importance in GWAS - Lecture 4 H3ABioNet 2018 GWAS Lecture series

, 2018
Quality control and its importance in GWAS In the fourth of a series of seven H3ABioNet online lectures for Genome Wide Association Studies (GWAS), the importance of doing good quality control for a GWAS will be discussed.
Shaun Aron (3186537)
core   +1 more source

Sensitivity and Criterion Validity of ED100K Lifetime Eating Disorder Diagnoses: A Study Using a National Eating Disorder Quality Register

International Journal of Eating Disorders, EarlyView.
ABSTRACT Background Epidemiological and genomic studies of eating disorders (ED) require scalable approaches to case ascertainment. The self‐report ED100K questionnaire assesses lifetime ED diagnoses, has been translated into several languages, and has been used in large cohort studies, with data shared or planned for sharing through major repositories
Hunna J. Watson, Andreas Birgegård, Liv Hog, Lisa Dinkler, Emma Forsén Mantilla, Laura M. Thornton, Cynthia M. Bulik   +6 more
wiley   +1 more source

Pharmacogenomics And Hypertension: Current Insights

Pharmacogenomics and Personalized Medicine, 2019
Gustavo H Oliveira-Paula,1,2 Sherliane C Pereira,2 Jose E Tanus-Santos,2 Riccardo Lacchini3 1Department of Medicine, Division of Cardiology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, New York, NY, USA ...
Oliveira-Paula GH, Pereira SC, Tanus-Santos JE, Lacchini R   +3 more
doaj  

Genomic selection accuracy for the yield trait in alfalfa half-sib families based on GWAS strategies

Grass Research
Alfalfa (Medicago sativa L.), a globally vital perennial forage supporting livestock, faces stagnant yield improvement due to polyploid complexity and slow genetic gains.
Yangyang Han, Bao Ao, Fan Zhang, Song Jing, Pan Xu, Qi Yan, Boyu Chu, Jiyu Zhang   +7 more
doaj   +1 more source