Results 121 to 130 of about 283,327 (339)

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

The IIIVmrMLM method uncovers new genetic variants associated with resistance to Fusarium wilt in flax

Вавиловский журнал генетики и селекции
Flax (Linum usitatissimum) is an important agricultural crop grown for fiber and oil production, playing a key role in various industries such as production of paints, linoleum, food, clothes and composite materials.
M. A. Duk, A. A. Kanapin, A. A. Samsonova, M. P. Bankin, M. G. Samsonova   +4 more
doaj   +1 more source

Crick’s sequence hypothesis - a review

Communicative & Integrative Biology, 2019
Health care based on gene sequencing and genomics is increasingly becoming a reality: it is timely to review Crick’s sequence hypothesis for its fitness for this purpose.
Keith Baverstock
doaj   +1 more source

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. [PDF]

, 2011
BackgroundRheumatoid arthritis (RA) can be divided into two major subsets based on the presence or absence of antibodies to citrullinated peptide antigens (ACPA).
Alfredsson, Lars, Ding, Bo, Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study group, Klareskog, Lars, Ong, Rick TH, Padyukov, Leonid, Rönnelid, Johan, Seddighzadeh, Maria, Seielstad, Mark   +8 more
core  

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

Updates on Genes and Genetic Mechanisms Implicated in Primary Angle-Closure Glaucoma

The Application of Clinical Genetics, 2021
Altaf A Kondkar1– 3 1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2Glaucoma Research Chair in Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 3King Saud University ...
Kondkar AA
doaj  

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Nature Neuroscience, 2018
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders.
R. Walters, R. Polimanti, Emma C. Johnson, J. McClintick, M. Adams, Amy E Adkins, F. Aliev, S. Bacanu, A. Batzler, S. Bertelsen, J. Biernacka, T. Bigdeli, Li-Shiun Chen, Toni‐Kim Clarke, Yi-Ling Chou, F. Degenhardt, A. Docherty, Alexis C. Edwards, P. Fontanillas, J. Foo, Louis Fox, J. Frank, I. Giegling, S. Gordon, L. Hack, A. Hartmann, Sarah M. Hartz, S. Heilmann-Heimbach, S. Herms, C. Hodgkinson, P. Hoffmann, Jouke Jan Hottenga, M. Kennedy, Mervi Alanne-Kinnunen, B. Konte, J. Lahti, M. Lahti-Pulkkinen, D. Lai, L. Ligthart, A. Loukola, B. Maher, H. Mbarek, A. McIntosh, M. McQueen, J. Meyers, Y. Milaneschi, T. Palviainen, J. Pearson, Roseann E. Peterson, S. Ripatti, E. Ryu, N. Saccone, J. Salvatore, S. Sanchez-Roige, M. Schwandt, R. Sherva, F. Streit, J. Strohmaier, N. Thomas, Jen C. Wang, B. Webb, Robbee Wedow, L. Wetherill, Amanda G. Wills, J. Boardman, Danfeng Chen, D. Choi, William E. Copeland, R. Culverhouse, N. Dahmen, L. Degenhardt, B. Domingue, S. Elson, M. Frye, Wolfgang Gäbel, C. Hayward, M. Ising, M. Keyes, F. Kiefer, J. Kramer, S. Kuperman, S. Lucae, M. Lynskey, W. Maier, K. Mann, S. Männistö, B. Müller-Myhsok, A. Murray, J. Nurnberger, A. Palotie, U. Preuss, K. Räikkönen, M. Reynolds, M. Ridinger, N. Scherbaum, M. Schuckit, M. Soyka, J. Treutlein, S. Witt, N. Wodarz, P. Zill, Daniel E. Adkins, J. Boden, D. Boomsma, L. Bierut, S. Brown, K. Bucholz, S. Cichon, E. Costello, H. de Wit, N. Diazgranados, D. Dick, J. Eriksson, L. Farrer, T. Foroud, N. Gillespie, A. Goate, D. Goldman, R. Grucza, D. Hancock, K. Harris, A. Heath, V. Hesselbrock, J. Hewitt, Christian J. Hopfer, J. Horwood, W. Iacono, Eric O. Johnson, J. Kaprio, V. Karpyak, K. Kendler, H. Kranzler, K. Krauter, P. Lichtenstein, P. Lind, M. McGue, J. Mackillop, P. Madden, H. Maes, P. Magnusson, N. Martin, S. Medland, G. Montgomery, E. Nelson, M. Nöthen, A. Palmer, N. Pedersen, B. Penninx, B. Porjesz, J. Rice, M. Rietschel, B. Riley, R. rose, D. Rujescu, Pei-Hong Shen, J. Silberg, M. Stallings, R. Tarter, M. Vanyukov, S. Vrieze, T. Wall, J. Whitfield, Hongyu Zhao, B. Neale, J. Gelernter, H. Edenberg, A. Agrawal   +166 more
semanticscholar   +1 more source

Genome‐Wide Association Analyses Reveal the Genetic Basis of EMS Mutagenesis Efficiency in Rice

Advanced Science, EarlyView.
Based on large‐scale screening of 420 rice accessions, GWAS identified the Rc locus as a key regulator of EMS mutagenesis efficiency. Functional Rc alleles enhance both seed survival and genome‐wide mutation frequency by boosting antioxidant enzyme activities (CAT, SOD, POD) and reducing oxidative damage.
Peizhou Xu, Qinglu Zhang, Le Xue, Zhen Zhang, Nanhui Luo, Zhaoyang Cheng, Duo Xia, Shuqin Zheng, Xianjun Wu, Hao Zhou   +9 more
wiley   +1 more source

Enhancer Dysfunction in 3D Genome and Disease

Cells, 2019
Spatiotemporal patterns of gene expression depend on enhancer elements and other factors during individual development and disease progression. The rapid progress of high-throughput techniques has led to well-defined enhancer chromatin properties ...
Ji-Han Xia, Gong-Hong Wei
doaj   +1 more source

Multi-trait GWAS using high-density genotypes identifies genes associated with body traits in Nile tilapia [PDF]

, 2020
Grazyella Yoshida, José M. Yáñez
openalex   +1 more source